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- 1Cardiac biomarkers
- 1Cardiac resynchronization therapy
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- 1Heart failure with reduced ejection fraction
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Assessment of the Utility and Impact of IV Magnesium Infusion on Patient Outcomes and Quality of Life in Acute Heart Failure
DownloadFall 2024
Heart failure (HF) is a complex condition which is a growing and lethal public health issue in Canada and internationally. In the last several decades, the number of treatments for HF with reduced ejection fraction, which makes up a large portion of the HF population, has grown. The recommended...
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Fall 2013
Heart failure is common, and is associated with significant mortality, morbidity, and reduced quality of life. The objective of this thesis is to evaluate some therapeutic interventions and outcomes in patients with acute and chronic heart failure. In the first part, the efficacy of cardiac...
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Multiple Outcomes in Heart Failure Research: Composite Endpoints and Multivariate Modelling
DownloadFall 2017
Composite endpoints are increasingly popular outcomes in clinical trials of heart failure. Uptake has outpaced guidance on their use and little consistency is seen in their construction. We must consider how best to handle multiple outcomes statistically and clinically, ie in a way that is both...