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Skip to Search Results- 1Alexander, Anthony John.
- 1Allen, Felicity R
- 1Black, Brenna A
- 1Blackmore, Derrick
- 1Borzouie, Shima
- 1Boyd, Jessica M.
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Breaking the wall of silence of trees Mining metabolomics to describe hybridization and predict performance in the Populus – Sphaerulina musiva pathosystem
DownloadFall 2017
Stem canker diseases in poplars caused by the fungal pathogen Sphaerulina musiva Peck. remain some of the least understood forest diseases despite causing considerable damage, particularly in hybrid poplar plantations. S. musiva is endemic to eastern Canada in provinces including the Maritimes,...
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Fall 2010
This thesis describes the application of mass spectrometry (MS) to glycoprotein and oligosaccharide analysis. Glycosylated proteins are involved in cell-cell and cell-matrix recognition. Applications of trypsin and proteinase K to hydrolyze glycoproteins into glycopeptides that are compatible...
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Characterization of glycosyltransferases and glycosidases using electrospray mass spectrometry
DownloadFall 2011
Carbohydrates are one of the major classes of organic compounds found in nature and living organisms, and the diverse roles of carbohydrates are crucial for most life forms. The transformation and degradation of glycans are effectively regulated by carbohydrate-modifying enzymes. This thesis...
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Spring 2015
The objective of this work was to employ differential 13C/12C dansyl chloride (DnsCl) derivatization strategies for qualitative and quantitative profiling of amine- and phenol-containing metabolites by liquid chromatography electrospray ionization Fourier Transform ion cyclotron resonance mass...
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Fall 2018
Metabolomics is the ultimate reflection of organisms influenced by both genetic and environmental factors. Compared with other omics areas, it is the most appropriate and closest description of phenotype, which is the comprehensive characteristics of an organism. It is a powerful tool for global...
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Spring 2016
One of the key obstacles to the effective use of mass spectrometry (MS) in high throughput metabolomics is the difficulty in interpreting measured spectra to accurately and efficiently identify metabolites. Traditional methods for automated metabolite identification compare the target MS spectrum...
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Spring 2014
Metabolomics involves the high throughput characterization of small molecules or metabolites in cells, tissues and organisms. To interpret, store and exchange metabolomic data it is necessary to have comprehensive, electronically accessible databases that can be used to handle both the...
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Fall 2011
Metabolomics aims to study all small-molecule compounds (i.e. metabolites) in cells, tissues, or biofluids. These compounds provide a functional readout of the physiological, developmental, and pathological state of a biological system. The field of metabolomics has expanded rapidly over the last...