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Skip to Search Results- 5Fliegel, Larry
- 5Sykes, Brian D.
- 3Chamot, Danuta
- 3Li, Xiuju J.
- 3Owttrim, George W.
- 3Owttrim, George W.
- 11Biological Sciences, Department of
- 11Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 5Biochemistry, Department of
- 5Biochemistry, Department of/Journal Articles (Biochemistry)
- 4Graduate and Postdoctoral Studies (GPS), Faculty of
- 4Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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1999
Owttrim, George W., Magee, Wendy C., Yu, Esther, Chamot, Danuta
The ability to modify RNA secondary structure is crucial for numerous cellular processes. We have characterized two RNA helicase genes, crhB and crhC, which are differentially expressed in the cyanobacterium Anabaena sp. strain PCC 7120. crhC transcription is limited specifically to cold shock...
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A LexA-related protein regulates redox-sensitive expression of the cyanobacterial RNA helicase, crhR
Download2006
Colvin, Kimberley R., Owttrim, George W. , Patterson-Fortin, Laura M.
Expression of the cyanobacterial DEAD-box RNA helicase, crhR , is regulated in response to conditions, which elicit reduction of the photosynthetic electron transport chain. A combination of electrophoretic mobility shift assay (EMSA), DNA affinity chromatography and mass spectrometry identified...
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Characterization of the Type VI Secretion System in the Bacterial Pathogen Acinetobacter baumannii
DownloadFall 2016
Antibiotic resistant bacteria that cause hospital-acquired infections are a mounting concern for healthcare systems globally. Multidrug resistant (MDR) Acinetobacter baumannii has emerged as a common cause of nosocomial infections, and some isolates are now pandrug resistant. These infections can...
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Comparative analysis of two phenotypically-similar but genomically-distinct Burkholderia cenocepacia-specific bacteriophages
Download2012
Stothard, Paul, Dennis, Jonathan J., Lynch, Karlene H.
Background Genomic analysis of bacteriophages infecting the Burkholderia cepacia complex (BCC) is an important preliminary step in the development of a phage therapy protocol for these opportunistic pathogens. The objective of this study was to characterize KL1 (vBBceSKL1) and AH2 (vBBceSAH2),...
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Conditional, temperature-induced proteolytic regulation of cyanobacterial RNA helicase expression
Download2014
Owttrim, George W., Tarassova, Oxana S., Chamot, Danuta
Conditional proteolysis is a crucial process regulating the abundance of key regulatory proteins associated with the cell cycle, differentiation pathways, or cellular response to abiotic stress in eukaryotic and prokaryotic organisms. We provide evidence that conditional proteolysis is involved...
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Corynebacterium glutamicum: A Platform For Studying Actinobacterial Protein-O-Mannosylation And High-Yield Heterologous Protein Production
DownloadSpring 2024
Corynebacterium glutamicum ATCC 13032 is a generally regarded as safe (GRAS) soil actinobacterium that is widely utilized in industry and was originally used for the large-scale production of amino acids. Through both genetic and metabolic engineering, the organism has been developed into a...
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Cyanobacterial RNA Helicase CrhR Localizes to the Thylakoid Membrane Region and Cosediments with Degradosome and Polysome Complexes in Synechocystis sptrain PCC 6803
Download2016
Fahlman, Richard P., Owttrim, George W. , Rosana, Albert R. R., Whitford, Denise S.
The cyanobacterium Synechocystis sp. strain PCC 6803 encodes a single DEAD box RNA helicase, CrhR, whose expression is tightly autoregulated in response to cold stress. Subcellular localization and proteomic analysis results indicate that CrhR localizes to both the cytoplasmic and thylakoid...
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Designed zinc finger proteins as novel therapeutics inhibiting the transcription of hepatitis B and duck hepatitis B viruses
DownloadFall 2010
The Hepatitis B virus (HBV) chronically infects 350 million individuals worldwide, leading to mortality by end-stage liver disease, liver cirrhosis, and hepatocellular carcinoma. The vaccine to prevent HBV infection is highly effective but is not extensively available in endemic areas, resulting...
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Differential exudation of polypeptides by roots of aluminum-resistant and aluminum-sensitive cultivars of Triticum aestivum L. in response to aluminum stress
Download1994
Basu, A., Taylor, G. J., Basu, U.
Cultivars of Triticum aestivum differing in resistance to Al were grown under aseptic conditions in the presence and absence of Al and polypeptides present in root exudates were collected, concentrated, and analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Upon exposure to...