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- 14Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
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Hippocampal neuroplasticity and neurogenesis in major depressive disorder: a high field MRI study
DownloadFall 2012
The hippocampus is a brain structure responsible for memory, learning, and the stress response; it is also used as a model for major depressive disorder (MDD) in preclinical studies. Preclinical models have shown that the hippocampal subfields are differentially affected by chronic stress....
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Spring 2016
Image segmentation is the problem of assigning 2D pixels or 3D voxels to a set of finite labels. In particular, in medical imaging, the goal of segmentation is to partition an MRI or CT image into regions that are relevant to the biology of a particular disease, for example the motor cortex in...
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Fall 2016
Understanding human immunodeficiency-1 (HIV-1) replication and latency in different reservoirs is an ongoing challenge in the care of patients with HIV/AIDS. A mathematical model was created that predicted HIV-1 and simian immunodeficiency virus (SIV) infection dynamics within the brain during...
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Fall 2014
The pairing of implantable micro-electrode arrays with micro-electronic devices allows the observation of neural activity within nervous systems in a more comprehensive and potentially more effective way compared to single electrode recording. State-of-the-art tethered recording systems use...
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The roles of Pbx and Meis TALE-class homeodomain transcription factors in vertebrate neural patterning
DownloadFall 2010
One of the major goals of developmental biology is to understand how specialized groups of cells arise from an initially unspecified cell population. The vertebrate hindbrain is transiently segmented along its anterior-posterior axis into lineage-restricted compartments called rhombomeres, making...