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Alteration of astrocyte markers and phosphorylation of tau protein in kainic acid-treated animal model of Temporal Lobe Epilepsy
DownloadFall 2022
Kainic acid, an analogue of the excitatory neurotransmitter glutamate, when administered systemically can trigger seizures and neuronal loss in a manner that mirrors the neuropathology of human mesial temporal lobe epilepsy (mTLE), which affects ~50million people globally. Evidence suggests that...
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Spring 2014
Recent technological advancements in the field of neural recording and decoding have changed the landscape of neural prostheses. However, a lack of biocompatible electrodes for long-term neural recording resulting in loss of electrode functionality is currently a major limiting factor for...
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09/24/2021
SSHRC IG awarded 2022: Videogames offer tremendous potential for more meaningful interactions with music and sound, but in most cases, the role that sound and music plays is subservient to the story or game world, rather than being a point of exploration in and of itself. What if composers...
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Spring 2011
Niemann-Pick Type C (NPC) disease is an autosomal recessive disorder that results in accumulation of unesterified cholesterol in late endosomes/lysosomes (LE/Ls), leading to progressive neurodegeneration and premature death. Microglia are resident immune cells of the central nervous system, which...
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Choosing versus receiving feedback: The impact of feedback valence on learning in an assessment game
Choosing versus receiving feedback: The impact of feedback valence on learning in an assessment game
2016
Studies examining feedback in educational settings have largely focused on feedback that is received, rather than chosen, by students. This study investigates whether adult participants learn more from choosing rather than receiving feedback from virtual characters in a digital poster design...
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Spring 2010
This study examined fairness in the online society of World of Warcraft(WoW), a society under constraint by game developers but dynamically affected by users. Because the society is voluntary, people have the ability to both effect major change on, and leave, that society at any time. Thus,...
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Fall 2015
A large volume of literature exists on fault detection and isolation for industrial processes. In a general view, these various methods may be divided into process model based and process history based fault diagnosis. In both classes, there has been a recent focus on extracting the temporal...
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Gesture Recognition using Hidden Markov Models, Dynamic Time Warping, and Geometric Template Matching
DownloadFall 2013
Gesture recognition is useful in many applications, including human-computer interaction, automated sign language recognition, medical applications, and many more. The main focus of this thesis is to improve the isolated gesture recognition accuracy of Hidden Markov Models (HMMs) and to provide a...
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Glial Expression of Amyloid Precursor Protein (APP) and its Processing Enzymes in the ANPC Mouse Model
DownloadFall 2021
Alzheimer’s disease (AD) is a complex and progressive neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ) peptides derived from the proteolytic processing of amyloid precursor protein (APP). The regions primarily affected in AD brains are the hippocampus and...