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Skip to Search Results- 1Alvarado, Laura
- 1Auriat, Angela Michelle
- 1Bamford, Jeremy, Andrew
- 1Bandet, Mischa V.
- 1Bergquist, Austin J
- 1Cheng,Cheng
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Influence of therapeutic hypothermia on neuroprotection and post-ischemic plasticity in a rat model of global ischemia
DownloadFall 2011
Blood flow to the brain may be disrupted by either a stroke (such as focal ischemia or hemorrhage) or cardiac arrest, where the whole brain becomes ischemic. Both forms of injury result in irreversible neuronal loss leading to neurological impairments and a decrease in the quality of life....
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Investigation of intermittent electrical stimulation as a potential prophylaxis against the formation of deep pressure ulcers after spinal cord injury
DownloadFall 2009
Deep tissue injury (DTI) is a severe form of pressure ulcers resulting from ischemia and mechanical damage due to unrelieved pressure. Despite many preventative methods, none so far has significantly reduced the incidence of DTI. The use of a novel method of pressure ulcer prevention,...
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Spring 2019
Walking is a locomotor task that integrates information from all over the nervous system. The lumbosacral spinal cord houses neural networks that contribute to locomotion. These networks dominate locomotor activity during development and may provide suitable targets for restoring function after...
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Fall 2021
Spinal cord injury (SCI) not only leads to motor and sensory dysfunction, but just as debilitating are secondary consequences of SCI such as bowel disorders, neuroinflammation, immune suppression, pain and psychiatric disorders. In this thesis, I explore multiple aspects of recovery after SCI in...
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Middle-Aged and Older Adult Walking and Hiking Groups of Cochrane, Alberta: How Outdoor Group Exercise Influences Perceptions of Health, Healing, and Disease
DownloadFall 2011
Middle-aged and older adult walking and hiking groups of Cochrane had unique perceptions of health and healing due to their activities, the equipment they used, the environments they explored, and the relationships they developed. Past anthropological research has focused on aging, ethnomedicine,...
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MODELING INCOMPLETE CERVICAL SPINAL CORD INJURY IN RATS TO EXPLORE MECHANISMS OF REHABILITATIVE TRAINING
DownloadFall 2013
Although limited functional recovery is observed following spinal cord injury (SCI), the most successful approach to promote recovery to date has been rehabilitative training. However, the effects of training are not stunning. With a thorough understanding of the intracellular mechanisms involved...
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Motor unit recruitment by intraspinal microstimulation and long-term neuromuscular adaptations
DownloadFall 2009
Spinal cord injury is a devastating neurological disorder partially characterized by a loss of motor function below the lesion. The dramatic loss of activity results in muscle atrophy and slow-to-fast transformation of contractile elements, producing smaller, weaker and more fatiguable muscles....
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Neuronal Mechanisms of Hyperexcitability in Individuals with Spasticity after Spinal Cord Injury and Individuals with Bruxism
DownloadFall 2013
Motoneuron hyperexcitability is a characteristic of several different motor disorders. We examined neuronal mechanisms of hyperexcitability in two of these disorders: spasticity after spinal cord injury (SCI) and bruxism. Involuntary muscle spasms after SCI occur as a result of uncontrolled...
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Fall 2015
Inhibitory feedback from sensory pathways is important for controlling movement. In this thesis we characterize a long-latency inhibitory spinal pathway to ankle flexors that is activated by low-threshold, homonymous afferents. In non-injured participants, this pathway was activated by both...
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Fall 2023
The overarching idea of this thesis stemmed from previous work in our lab, where it was noticed that females and males exhibited different disease trajectories in a model of Multiple Sclerosis. Combined with our observation of different outcome metrics for peripheral nociception suggested that...