Search
Skip to Search Results- 3Löbenberg, Raimar
- 2Azarmi, Shirzad
- 2Finlay, Warren H.
- 2Roa, Wilson
- 1Dennis, Jonathan J.
- 1Dickau, Matthew A
- 15Graduate and Postdoctoral Studies (GPS), Faculty of
- 15Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 3Pharmacy and Pharmaceutical Sciences, Faculty of
- 3Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy and Pharmaceutical Sciences)
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
-
Spring 2018
The centrifugal particle mass analyzer (CPMA)-electrometer system has been proposed as an alternative method of calibration for devices that measure black carbon. This system is proposed to replace the current calibration standard of NIOSH 5040. The repeatability and intermediate precision of the...
-
Fall 2020
Infectious respiratory diseases, caused by viruses and bacteria that attack the respiratory system, constitute a serious threat in public health around the world. Pathogens can be transmitted in the air though large droplets or aerosols. As aerosols can linger in the environment for a prolonged...
-
Study of Enhanced Deposition due to Magnetic Field Alignment of Ellipsoid Particles Using Direct Numerical Simulations
DownloadFall 2012
A recent in vitro study demonstrated a non invasive method to enhance local deposition in a small airway by controlling the angular position of magnetic high aspect ratio particles. This technique could mitigate the challenge of providing sufficient therapeutic effects when using aerosolized...
-
The [1,2]-Stevens Rearrangement of Oxonium Ylides: Synthetic Applications and Mechanistic Studies
DownloadSpring 2016
The Stevens [1,2]-rearrangement of onium ylides has been employed as a valuable synthetic method to construct new C-C bonds. Oxonium ylides are reactive intermediates that undergo facile Stevens rearrangement under mild conditions. In the last several decades, the Stevens rearrangement of oxonium...
-
The mechanism of action of cidofovir and (S)-9-(3-hydroxy-2-phosphonomethoxypropyl)adenine against viral polymerases
DownloadFall 2009
The nucleoside phosphonates cidofovir (CDV) and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine [(S)-HPMPA] are analogs of dCMP and dAMP, respectively. Collectively these drugs are effective inhibitors of a wide range of DNA viruses, RNA viruses, and retroviruses. Because they are nucleotide...
-
Toward Modern Inhalational Bacteriophage Therapy: Nebulization of Bacteriophages of Burkholderia cepacia Complex
Download2008
Dennis, Jonathan J., Finlay, Warren H., Golshani, Laleh, Seed, Kimberley D.
Antibiotic-resistant bacterial infections have renewed interest in finding substitute methods of treatment. The purpose of the present in vitro study was to investigate the possibility of respiratory delivery of a Burkholderia cepacia complex (BCC) bacteriophage by nebulized aerosol...
-
Spring 2011
Most current models for the deposition of aerosol particles in the human lung are based on a Lagrangian reference frame, which is ill-suited for modeling transient eects. Deposition models based on an Eulerian reference frame are much better at capturing instantaneous time-dependent eects, though...
-
Treatment of Antiviral Drugs in Wastewater Using Advanced Oxidation Processes - Ozonation of Oseltamivir Phosphate
DownloadFall 2021
While wastewater treatment facilities are designed to remove contaminants from water before it returns to the environment, unfortunately, not all of these facilities are effective in the removal of micropollutants (MPs). Antiviral drugs are a class of MPs that have become an area of concern due...