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Skip to Search Results- 3Boyd, T. J. M.
- 3Deyholos, Michael K.
- 3Fliegel, Larry
- 2Barr, H. C.
- 2Harrington, Michael J.
- 2Hegele, Robert A.
- 36Graduate and Postdoctoral Studies (GPS), Faculty of
- 36Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 12Biological Sciences, Department of
- 9Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 36Thesis
- 27Article (Published)
- 3Book
- 2Research Material
- 1Article (Draft / Submitted)
- 1Learning Object
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2000-08-01
Wang, Jian, Burnett, John R., Near, Susan, Young, T. Kue, Zinman, Bernard, Hanley, Anthony J. G., Connelly, Philip W., Harris, Stewart B., Hegele, Robert A.
"Mutations in ABCA1, a member of the ATP-binding cassette family, have been shown to underlie Tangier disease (TD) and familial hypoalphalipoproteinemia (FHA), which are genetic disorders that are characterized by depressed concentrations of plasma high density lipoprotein (HDL) cholesterol. An...
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Common variants APOC3, APOA5, APOE and PON1 are associated with variation in plasma lipoprotein traits in Greenlanders
Download2007-12-01
Lahiry, Piya, Ban, Matthew R., Pollex, Rebecca L., Sawyez, Cynthia G., Huff, Murray W., Young, T. Kue, Bjerregaard, Peter, Hegele, Robert A.
"Objectives: We undertook studies of the association between common genomic variations in APOC3, APOA5, APOE and PON1 genes and variation in biochemical phenotypes in a sample of Greenlanders. Study Design: Genetic association study of quantitative lipoprotein traits. Methods: In a sample of...
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2019-01-01
Nair, Sindhu G., Loppnow, Glen R.
It has been well established that mutations in K-Ras and N-Ras proto-oncogenes can convert them into active oncogenes. Current molecular cancer research has been focused on determining the key steps by which cellular genes become oncogenes and not on the underlying and fundamental chemical damage...
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Fall 2012
To understand the water cycle on Mars, details of mass and energy transfer between the surface and the atmosphere are of importance. A complete model, involving transient variations of the water in gaseous and solid phases in the atmosphere and the regolith, is developed and solved numerically...
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Contribution to the taxonomy of Oxytropis campestris (L.) DC. in northwestern North America
Download1978
Masters thesis. Suggests elevation of five taxa of Oxytropis campestris to species status, based on chromosome studies.
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Fall 2014
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...
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Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair
Download2011
Tiong, S., McKim, K.S., Campbell, S.D., White-Brown, S.K., Paul, A., Pedersen, M., Joyce, E.F.
Ataxia telangiectasia–mutated (ATM) and ataxia telangiectasia–related (ATR) kinases are conserved regulators of cellular responses to double strand breaks (DSBs). During meiosis, however, the functions of these kinases in DSB repair and the deoxyribonucleic acid (DNA) damage checkpoint are...
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Electrophysiological and Genetic Aspects of Age-Related Macular Degeneration (AMD): Treatment Implications
DownloadFall 2014
Age-related macular degeneration (AMD) is considered a heterogeneous group of disorders. Although many genes influence susceptibility to disease, none has shown to be the primary contributor. To identify genetic contributors, distinct AMD phenotypes need to be established. We relied on...
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Emerging pathways in the regulation of whole body cholesterol flux: Therapeutic opportunities to target atherosclerosis?
Download2014
Mangat, Rabban, Proctor, Spencer D.
INTRODUCTION: CVD remains one of the most frequent causes of morbidity and mortality globally. Increased awareness of lifestyle factors (nutrition/exercise), as well as the refinement of lipid-lowering therapies, has availed some progress in reducing the incidence of CVD. Historically, the...
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2006
Wilson, A.J., Pemberton, J.M., Coltman, D.W., Kruuk, L.E.B., Pilkington, J.G., Mifsud, D.V., Clutton-Brock, T.H.
There has recently been great interest in applying theoretical quantitative genetic models to empirical studies of evolution in wild populations. However, while classical models assume environmental constancy, most natural populations exist in variable environments. Here, we applied a novel...