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Skip to Search Results- 4Wu, Jianping
- 3Chakrabarti, Subhadeep
- 3Majumder, Kaustav
- 2Bergen, Werner G.
- 2Davidge, Sandra T.
- 2Dodson, Michael V.
- 9Agricultural, Food and Nutritional Science, Department of
- 9Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 8Graduate and Postdoctoral Studies (GPS), Faculty of
- 8Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 1School of Public Health
- 1School of Public Health/Journal Articles (Public Health)
- 1Department of Biological Sciences
- 1Department of Oncology
- 1Department of Physiology
- 1Faculty of Kinesiology, Sport, and Recreation
- 1Faculty of Pharmacy and Pharmaceutical Sciences
- 1Faculty of Physical Education and Recreation
- 1Bell, Gordon (Physical Education and Recreation)
- 1Carlos A Velázquez (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Davidge, Sandra (dept. of Physiology)
- 1DeLorey, Darren Faculty of Kinesiology, Sport, and Recreation
- 1DeLorey, Darren S. (Physical Education and Recreation)
- 1Fu, YangXin (Department of Obstetrics & Gynecology, Department of Oncology)
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1999-01-01
Xie, Changping, Albrecht, Elke, Wegner, Jochen J., Brockmann, Gudrun A., Kazala, Christopher, Weselake, Randall J., Ender, Klaus
Leptin is a hormone involved in the regulation of feed intake and energy balance in animals. The expression and secretion of leptin is highly correlated with body fat mass and adipocyte size. The regulation of leptin is integrated into a broad regulatory network including other hormones and...
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Lipid metabolism, adipocyte depot physiology and utilization of meat animals as experimental models for metabolic research
Download2010-01-01
Dodson, Michael V., Hausman, Gary J., Guan, LeLuo, Du, Min, Rasmussen, Theodore P., Poulos, Sylvia P., Mir, Priya, Bergen, Werner G., Fernyhough, Melinda E., McFarland, Douglas C., Rhoads, Robert P., Soret, Beatrice, Reecy, James M., Velleman, Sandra G., Jiang, Zhihua
Meat animals are unique as experimental models for both lipid metabolism and adipocyte studies because of their direct economic value for animal production. This paper discusses the principles that regulate adipogenesis in major meat animals (beef cattle, dairy cattle, and pigs), the definition...
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Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) promote adipocyte differentiation and inhibit inflammation in 3T3-F442A cells
Download2015
Chakrabarti, Subhadeep, Wu, Jianping
Milk derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) have shown promise as anti-hypertensive agents due to their inhibitory effects on angiotensin converting enzyme (ACE). Due to the key inter-related roles of hypertension, chronic inflammation and insulin resistance in the...
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Molecular targets of antihypertensive peptides: Understanding the mechanisms of action based on the pathophysiology of hypertension
Download2015
Majumder, Kaustav, Wu, Jianping
There is growing interest in using functional foods or nutraceuticals for the prevention and treatment of hypertension or high blood pressure. Although numerous preventive and therapeutic pharmacological interventions are available on the market, unfortunately, many patients still suffer from...
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Notch regulates the growth-promoting nitric oxide cGMP-dependent pathway in epithelial ovarian cancer and ovarian surface epithelium cells
DownloadSpring 2014
El-Sehemy, Ahmed Ali Ahmed Ali
Ovarian cancer is the leading cause of mortality among gynecologic cancers. There are several subtypes of ovarian cancer, amongst which epithelial ovarian cancer (EOC) makes up to 90% of all ovarian cancers. The current treatment for EOC consists of debulking surgery followed by a...
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NSAID Prodrugs with Improved Anti-inflammatory Activity and Low Ulcerogenicity: Wake Up Call to Pharmaceutical Companies and Health Authorities
DownloadSpring 2012
The objective of this work was to synthesize and evaluate the biological properties of a new series of nitric oxide-releasing non-steroidal anti-inflammatory drugs (NO-NSAIDs) possessing a tyrosol linker between the carboxylic acid present in classical NSAIDs and a NO-releasing group (PROLI/NO)...
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Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk
Download2014-01-01
Huyard, Fanny, Yzydorczyk, Catherine, Castro, Michele M., Cloutier, Anik, Bertagnolli, Mariane, Sartelet, Hervé, Schulz, Richard, Nuyt, Anne Monique
Neonatal high-oxygen exposure leads to elevated blood pressure, microvascular rarefaction, vascular dysfunction and arterial (aorta) rigidity in adult rats. Whether structural changes are present in the matrix of aorta wall is unknown. Considering that elastin synthesis peaks in late fetal life...
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2010-01-01
Dodson, Michael V., Hausman, Gary J., Guan, LeLuo, Du, Min, Rasmussen, Theodore P., Poulos, Sylvia P., Mir, Priya, Bergen, Werner G., Fernyhough, Melinda E., McFarland, Douglas C., Rhoads, Roberts P., Soret, Beatrice, Reecy, James M., Velleman, Sandra G., Jiang, Zhihua
Skeletal muscle stem cells from food-producing animals are of interest to agricultural life scientists seeking to develop a better understanding of the molecular regulation of lean tissue (skeletal muscle protein hypertrophy) and intramuscular fat (marbling) development. Enhanced understanding of...
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The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption in High-fit and Untrained Individuals
DownloadFall 2019
Previous work suggests that endurance-trained athletes have superior pulmonary vasculature function as compared to untrained individuals, which may contribute to their greater maximal oxygen uptake (V̇O2max). Inhaled nitric oxide (iNO) improves pulmonary vascular compliance at rest in healthy...