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Skip to Search Results- 1Bekele, Raie T.
- 1Benesch, Matthew
- 1Brindley, David N.
- 1Curtis, Jonathan M.
- 1Godbout, Roseline
- 1Liu, Rong-Zong
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Oxidative stress mediates estrogen receptor independent killing and contributes to tamoxifen resistance
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Godbout, Roseline, Brindley, David N., McMullen, Todd, Mackey, John R., Benesch, Matthew, Mi, Si, Venkatraman, Ganesh, Liu, Rong-Zong, Curtis, Jonathan M., Tang, Xiaoyun, Bekele, Raie T.
Tamoxifen is the accepted therapy for patients with estrogen receptor-α (ERα)-positive breast cancer. However, clinical resistance to tamoxifen, as demonstrated by recurrence or progression on therapy, is frequent and precedes death from metastases. To improve breast cancer treatment it is vital...