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Skip to Search Results- 37Stothard, Paul
- 20Plastow, Graham S.
- 9Bao, Hua
- 9Harding, John C. S.
- 8Dekkers, Jack C. M.
- 8Lunney, Joan K.
- 29Agricultural, Food and Nutritional Science, Department of
- 29Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 13PigGen Canada
- 13PigGen Canada/Journal Articles
- 7Roy Berg Kinsella Research Ranch
- 7Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
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2012
Stothard, Paul, Arantes, Adriano S., Grant, Jason R.
Background Continued sequencing efforts coupled with advances in sequencing technology will lead to the completion of a vast number of small genomes. Whole-genome comparisons represent an important part of the analysis of any new genome sequence, as they can provide a better understanding of the...
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Comparison of host genetic factors influencing pig response to infection with two North American isolates of porcine reproductive and respiratory syndrome virus
Download2016-01-01
Hess, Andrew S., Islam, Zeenath, Hess, Melanie K., Rowland, Raymond R. R., Lunney, Joan K., Doeschl-Wilson, Andrea, Plastow, Graham S., Dekkers, Jack C. M.
Background:Porcine reproductive and respiratory syndrome (PRRS) is one of the most important swine diseases in the world and genetic selection of pigs for increased resistance to PRRS is an attractive method to improve the health status of the swine herd. This study compared phenotypic and...
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Differences in whole blood gene expression associated with infection time-course and extent of fetal mortality in a reproductive model of type 2 porcine reproductive and respiratory syndrome virus (PRRSV) infection
Download2016
Ladinig, Andrea, Stothard, Paul, Wilkinson, Jamie M., Kommadath, Arun, Plastow, Graham S., Harding, John C. S., Bao, Hua, Lunney, Joan K.
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant females causes fetal death and increased piglet mortality, but there is substantial variation in the extent of reproductive pathology between individual dams. This study used RNA-sequencing to characterize the whole...
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Differences in Whole Blood Gene ExpressionAssociated with Infection Time-Course andExtent of Fetal Mortality in a ReproductiveModel of Type 2 Porcine Reproductive andRespiratory Syndrome Virus (PRRSV)Infection
Download2016-04-19
Wilkinson, Jamie M., Ladinig, Andrea, Bao, Hua, Kommadath, Arun, Stothard, Paul, Lunney, Joan K., Harding, John C. S., Plastow, Graham S.
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnantfemales causes fetal death and increased piglet mortality, but there is substantial variationin the extent of reproductive pathology between individual dams. This study used RNA-sequencing to characterize the whole...
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2006
Chang, Zhan, Hassanali, Murtaza, Wishart, David S., Stothard, Paul, Woolsey, Jennifer, Guo, AnChi, Shrivistava, Savita, Knox, Craig
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug (i.e. chemical) data with comprehensive drug target (i.e. protein) information. The database contains >4100 drug entries including >800 FDA approved small molecule and biotech drugs as well as >3200...
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Exploring Phenotypes for Disease Resilience in Pigs Using Complete Blood Count Data From a Natural Disease Challenge Model
Download2020-01-01
Bai, Xuechun, Putz, Austin M., Wang, Zhiquan, Fortin, Frederic, Harding, John C. S., Dyck, Michael K., Dekkers, Jack C. M., Field, Catherine J., Plastow, Graham S., PigGen Canada
Disease resilience is a valuable trait to help manage infectious diseases in livestock. It is anticipated that improved disease resilience will sustainably increase production efficiency, as resilient animals maintain their performance in the face of infection. The objective of this study was to...
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2012
Wang, Lusheng, Moore, Steve S., Cai, Zhipeng, Goebel, Randy, Lin, Guohui, Wang, Yining, Stothard, Paul
Background Single nucleotide polymorphism (SNP) genotyping assays normally give rise to certain percents of no-calls; the problem becomes severe when the target organisms, such as cattle, do not have a high resolution genomic sequence. Missing SNP genotypes, when related to target traits, would...
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Genetic and genomic basis of antibody response to porcine reproductive and respiratory syndrome (PRRS) in gilts and sows
Download2016-01-01
Serao, Nick V. L., Kemp, Robert A., Mote, Benny E., Willson, Philip, Harding, John C. S., Bishop, Stephen C., Plastow, Graham S., Dekkers, Jack C. M.
Background:Our recent research showed that antibody response to porcine reproductive and respiratory syn-drome (PRRS), measured as sample-to-positive (S/P) ratio, is highly heritable and has a high genetic correlation with reproductive performance during a PRRS outbreak. Two major quantitative...
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Genetic architecture of gene expression underlying variation in host response to porcine reproductive and respiratory syndrome virus infection
Download2017-04-10
Kommadath, Arun, Bao, Hua, Choi, Igseo, Reecy, James M., Koltes, James E., Fritz-Waters, Elyn, Eisley, Chris J., Grant, Jason R., Rowland, Robert R. R., Tuggle, Christopher K., Dekkers, Jack C. M., Lunney, Joan K., Guan, Le Luo, Stothard, Paul, Plastow, Graham S.
It has been shown that inter-individual variation in host response to porcine reproductive and respiratory syndrome (PRRS) has a heritable component, yet little is known about the underlying genetic architecture of gene expression in response to PRRS virus (PRRSV) infection. Here, we integrated...
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Genome sequence and activity of KS10, a transposable phage of the Burkholderia cepacia complex
Download2008
Lynch, Karlene H., Shrivastava, Savita, Seed, Kimberley D., Goudie, Amanda D., Wishart, David S., Stothard, Paul, Dennis, Jonathan J.
Background The Burkholderia cepacia complex (BCC) is a versatile group of Gram negative organisms that can be found throughout the environment in sources such as soil, water, and plants. While BCC bacteria can be involved in beneficial interactions with plants, they are also considered...