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2018-01-05
Guo, Tianlin, Datwyler, Philipp, Demina, Ekaterina, Richards, Michele R, Ge, Peng, Zou, Chunxia, Zheng, Ruixiang Blake, Fougerat, Anne, Pshezhetsky, Alexey V, Ernst, Beat, Cairo, Christopher W.
Human neuraminidases (NEU) are associated with human diseases including cancer, atherosclerosis, and diabetes. To obtain small molecule inhibitors as research tools for the study of their biological functions, we designed a library of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues...