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Skip to Search Results- 10Wu, Jianping
- 5Chakrabarti, Subhadeep
- 3Majumder, Kaustav
- 2Davidge, Sandra T.
- 2Jahandideh, Forough
- 2Kaufman, Susan
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Beneficial effects of simulated gastro-intestinal digests of fried egg and its fractions on blood pressure, plasma lipids and oxidative stress in spontaneously hypertensive rats
Download2014
Majumder, Kaustav, Jahandideh, Forough, Morton, Jude S., Davidge, Sandra T., Kaufman, Susan, Chakrabarti, Subhadeep, Panahi, Sareh, Wu, Jianping
Background We have previously characterized several antihypertensive peptides in simulated digests of cooked eggs and showed blood pressure lowering property of fried whole egg digest. However, the long-term effects of this hydrolysate and its fractions on blood pressure are not known. Therefore,...
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Betulinic acid prevents alcohol-induced liver damage by improving the antioxidant system in mice
Download2014-01-01
Yi, Jine, Xia, Wei, Wu, Jianping, Yuan, Liyun, Wu, Jing, Tu, Di, Fang, Jun, Tan, Zhuliang
Betulinic acid (BA), a pentacyclic lupane-type triterpene, has a wide range of bioactivities. The main objective of this work was to evaluate the hepatoprotective activity of BA and the potential mechanism underlying the ability of this compound to prevent liver damage induced by alcohol in vivo....
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2016
Chakrabarti, Subhadeep, Wu, Jianping
Cardiovascular diseases (CVD) such as myocardial infarction and stroke are a major cause of morbidity and mortality worldwide. Impairment of the normal vasorelaxant functions of the vascular endothelium, termed endothelial dysfunction; appear to underlie the pathogenesis of CVD. Endothelial...
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Chemical modification, characterization, and application of chicken feathers as novel biosorbents
Download2013
Ullah, Aman, Khosa, Muhammad A., Wu, Jianping
The current work exclusively pertains to preparing arsenic removing biosorbents using chicken feathers (CF) as a raw material. CF consist of keratinous proteins with many functional groups, and this paper contributes to the debate on how functional groups, especially –COOH, –NH2 and –S–S–,...
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Egg-derived tri-peptide IRW exerts antihypertensive effects in spontaneously hypertensive rats
Download2013
Majumder, Kaustav, Kaufman, Susan, Chakrabarti, Subhadeep, Morton, Jude S., Panahi, Sareh, Wu, Jianping, Davidge, Sandra T.
Background There is a growing interest in using functional food components as therapy for cardiovascular diseases such as hypertension. We have previously characterized a tri-peptide IRW (Ile-Arg-Trp) from egg white protein ovotransferrin; this peptide showed anti-inflammatory, anti-oxidant and...
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2014
Chakrabarti, Subhadeep, Jahandideh, Forough, Wu, Jianping
Chronic diseases such as atherosclerosis and cancer are now the leading causes of morbidity and mortality worldwide. Inflammatory processes and oxidative stress underlie the pathogenesis of these pathological conditions. Bioactive peptides derived from food proteins have been evaluated for...
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2015
Nimalaratne, Chamila, Wu, Jianping
Intake of antioxidants through diet is known to be important in reducing oxidative damage in cells and improving human health. Although eggs are known for their exceptional, nutritional quality, they are not generally considered as antioxidant foods. This review aims to establish the importance...
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Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) promote adipocyte differentiation and inhibit inflammation in 3T3-F442A cells
Download2015
Chakrabarti, Subhadeep, Wu, Jianping
Milk derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) have shown promise as anti-hypertensive agents due to their inhibitory effects on angiotensin converting enzyme (ACE). Due to the key inter-related roles of hypertension, chronic inflammation and insulin resistance in the...
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Molecular targets of antihypertensive peptides: Understanding the mechanisms of action based on the pathophysiology of hypertension
Download2015
Majumder, Kaustav, Wu, Jianping
There is growing interest in using functional foods or nutraceuticals for the prevention and treatment of hypertension or high blood pressure. Although numerous preventive and therapeutic pharmacological interventions are available on the market, unfortunately, many patients still suffer from...
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2014
Proteomic analysis of egg white proteins was performed to elucidate their metabolic fates during first days of embryo development using 2-DE coupled with a LC–MS/MS. A total of 91 protein spots were analyzed, representing 37 proteins belonging to ‘Gallus gallus’, of 19 proteins were detected in...