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Skip to Search Results- 5Plastow, Graham
- 2Dekkers, Jack C. M.
- 2Field, Catherine J.
- 2Wang, Zhiquan
- 2Wilkinson, James
- 2Willing, Benjamin P.
- 2Microbiota
- 1Animal culture
- 1Antibiotic
- 1Complete blood count
- 1Disease resilience
- 1Genetic parameters
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A genome-wide association study of fetal response to type 2 porcine reproductive and respiratory syndrome virus challenge
Download2016-02-05
Plastow, Graham, Ladinig, Andrea, Harding, John, Wang, Zhiquan, Wilkinson, James, Yang, Tianfu
Control of porcine reproductive and respiratory syndrome (PRRS) is economically important for the swine industry worldwide. As current PRRS vaccines do not completely protect against heterologous challenge, alternative means of control, including enhanced genetic resilience, are needed. For...
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Discovery of Predictors of Mycoplasma hyopneumoniae Vaccine Response Efficiency in Pigs: 16S rRNA Gene Fecal Microbiota Analysis
Download2020-07-22
Munyaka, Peris M., Blanc, Fany, Estelle, Jordi, Lemonnier, Gaetan, Leplat, Jean-Jacques, Rossignol, Marie-Noelle, Jardet, Deborah, Plastow, Graham, Billon, Yvon, Willing, Benjamin P., Rogel-Gaillard, Claire
The gut microbiota comprises a large and diverse community of bacteria that play a significant role in swine health. Indeed, there is a tight association between the enteric immune system and the overall composition and richness of the microbiota, which is key in the induction, training and...
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Exploring Phenotypes for Disease Resilience in Pigs Using Complete Blood Count Data From a Natural Disease Challenge Model
Download2020-01-01
Bai, Xuechun, Putz, Austin M., Wang, Zhiquan, Fortin, Frederic, Harding, John C. S., Dyck, Michael K., Dekkers, Jack C. M., Field, Catherine J., Plastow, Graham S., PigGen Canada
Disease resilience is a valuable trait to help manage infectious diseases in livestock. It is anticipated that improved disease resilience will sustainably increase production efficiency, as resilient animals maintain their performance in the face of infection. The objective of this study was to...
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Genomic Prediction of Piglet Responses to Infection with One or Two Porcine Reproductive and Respiratory Syndrome Virus Isolates
Download2018-01-01
Waide, Emily H., Tuggle, Christopher K., Serao, Nick V. I., Schroyen, Martine, Hess, Andrew, Rowland, Raymond R. R., Lunney, Joan K., Plastow, Graham, Dekkers, Jack C. M.
Genomic prediction of the pig’s response to the porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) would be a useful tool in the swine industry. This study investigated the accuracy of genomic prediction based on porcine SNP60 Beadchip data using training and validation datasets...
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Kinome profiling of peripheral blood mononuclear cells collected prior to vaccination reveals biomarkers and potential mechanisms of vaccine unresponsiveness in pigs
Download2020-12-01
Lipsit, Sean W. L., Wilkinson, James, Scruten, Erin, Facciuolo, Antonio, Denomy, Connor, Griebel, Philip J., Kusalik, Anthony, Plastow, Graham, Napper, Scott
Inter-individual variance in host immune responses following vaccination can result in failure to develop protective immunity leaving individuals at risk for infection in addition to compromising herd immunity. While developing more efficacious vaccines is one strategy to mitigate this problem,...
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Neonatal Exposure to Amoxicillin Alters Long-Term Immune Response Despite Transient Effects on Gut-Microbiota in Piglets
Download2019-01-01
Fouhse, Janelle M., Yang, Kaiyuan, More-Bayona, Juan, Gao, Yanhua, Goruk, Susan, Plastow, Graham, Field, Catherine J., Barreda, Daniel R., Willing, Benjamin P.
Antibiotic exposure during neonatal development may result in transient or persistent alterations of key microbes that are vital for normal development of local and systemic immunity, potentially impairing immune competence later in life. To further elucidate the relationship between antibiotic...