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Skip to Search Results- 2Coulombe, Marilyne G.
- 2Kinnaird, Adam
- 2Srivastava, Nutan
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Aburahess, Salah
- 8Primary Biliary Cholangitis
- 7Inflammatory Bowel Disease
- 7Inflammatory bowel disease
- 6Endothelial cells
- 5Acute myeloid leukemia
- 5Mitochondria
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Fall 2024
Background: Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). Patients with CKD and CVD are often excluded from randomized control trials leading to a paucity of evidence guiding their care. This study leveraged province-wide...
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Fall 2024
The neighbourhood food environment, defined as the exposure to (measured as availability, density, or distance to) healthy and unhealthy food outlets around places within which individuals gravitate, including home, schools, workplaces, and beyond, plays a complex role in influencing food intake...
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Preventable errors in the performance and reporting of echocardiography and right heart catheterization can lead to diagnosis errors for pulmonary hypertension with significant implications for patients
DownloadFall 2024
Pulmonary hypertension (PH) is common and PH subgroups have vastly different mortality and treatment, particularly pulmonary arterial hypertension (PAH) versus PH secondary to heart failure with preserved ejection fraction (HFpEF). Both transthoracic echocardiography (TTE) and right heart...
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Assessment of the Utility and Impact of IV Magnesium Infusion on Patient Outcomes and Quality of Life in Acute Heart Failure
DownloadFall 2024
Heart failure (HF) is a complex condition which is a growing and lethal public health issue in Canada and internationally. In the last several decades, the number of treatments for HF with reduced ejection fraction, which makes up a large portion of the HF population, has grown. The recommended...
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Experience of patients with spinal cord injury regarding the quality of care during acute hospital stay in Nepal
DownloadFall 2024
Spinal Cord Injury (SCI) results in physical impairments, psychosocial issues, increased mortality and morbidity that challenge individuals and demand lifelong support, which starts from acute care. Understanding the experience after SCI in acute care is essential as it may impact the Person(s)...
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The Characterization and Assessment of Transition Success in Young Adults with Inflammatory Bowel Disease
DownloadFall 2024
Canada has one of the highest incidence rates of inflammatory bowel disease (IBD) worldwide, particularly among adolescents and young adults. As the incidence of pediatric-onset IBD is projected to increase in the upcoming years, more patients will need to transition from pediatric to adult care....
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Exposure to Allergens and Proinflammatory Mediators Modulate Airway Epithelial Cell Innate Responses, Metabolism, and Physiology
DownloadFall 2024
Lungs and airways health and protection depend on the integrity of airway epithelium. Insulin is a growth hormone that through activation of several signaling pathways play a central role to maintain cellular growth and activate metabolism. Airway epithelium is in constant exposure to inhaled...
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Mechanism and consequences of von Willebrand factor upregulation in response to aging and organ transplantation
DownloadFall 2024
Von Willebrand factor (VWF) is a procoagulant protein, which is crucial for blood clot formation and is exclusively expressed in endothelial cells and megakaryocytes. An unregulated increase in VWF levels is associated with elevating the incidence of thrombosis. Elevated VWF levels are observed...
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Referral, Appropriateness and Eligibility of Implantable Cardioverter Defibrillator Therapy in Alberta
DownloadSpring 2018
Background: Sudden cardiac death (SCD) is responsible for 50% of all cardiovascular deaths and is primarily due to rapid, life-threatening heart rhythm abnormalities. Multiple large, randomized clinical trials have demonstrated that implantable cardioverter defibrillator (ICD) therapy reduces...
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The Impact of Complications of Cirrhosis in Patients Undergoing Cardiac Surgery: A Propensity Matched Cohort Study
DownloadSpring 2018
Maria Xavier,Sagaya Jeya Sheela
Background: Patients with cirrhosis and concomitant coronary/valvular heart disease present a clinical dilemma. Cardiac surgeons often are reluctant to operate in this high-risk population, potentially diminishing survival/potential for liver transplant. This study aimed to identify associations...