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Skip to Search Results- 6Department of Chemistry
- 4Department of Electrical and Computer Engineering
- 3Department of Agricultural, Food, and Nutritional Science
- 2Department of Medicine
- 1Department of Agricultural, Food and Nutritional Science
- 1Department of Biochemistry
- 2Kurgan, Lukasz (Electrical and Computer Engineering)
- 1Ball, Ronald O. (Department of Agricultural, Food and Nutritional Science)
- 1Ballermann, Barbara (Medicine)
- 1Boekhoven, Job (Chemistry, Technical University of Munich)
- 1D. Jed Harrison (Chemistry)
- 1Dr. Barbara Ballermann (Department of Medicine, University of Alberta)
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Spring 2013
Moraes, Thania Gislaine Vasconcelos de
The effects of broiler breeder dietary energy and protein during rearing and dietary energy level of lay diets on egg composition, offspring performance and carcass yield were evaluated. Pullets were fed a diet containing high ME (2,736 kcal/kg; HEREAR), or low ME (2,528 kcal/kg; LEREAR) combined...
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Computational support systems for prediction and characterization of protein crystallization outcomes
DownloadFall 2013
Analysis of protein structures may reveal their function, regulation and interactions. Almost 90% of the known protein structures were solved using X-ray crystallography; however, many more structures remain unsolved. Protein Structure Initiative (PSI) project was created to speed up structure...
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Structure and dynamics of biomolecules: probing muscle regulation, prion protein unfolding, and drug insertion into DNA by nuclear magnetic resonance spectroscopy
DownloadSpring 2011
Nuclear magnetic resonance (NMR) spectroscopy is a powerful approach to study the structure and dynamics of macromolecules in a close-to-native solution environment. In the present thesis I present my investigation of protein and nucleic acid structure and dynamics in a wide variety of biological...
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Fall 2011
Proteins, which participate in virtually every process within cells, implement many of their functions through interactions with various ligands. Although a substantial effort in characterization and prediction of protein-ligand interactions was observed in the past two decades, these subjects...
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Spring 2010
The research presented in this work explores the application of microfluidics to the field of proteomics through the design of a multi-channel microfluidic platform and the investigation of individual components of the system. The design of this microfluidic device allows the integration of...
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An examination of linking and blocking procedures for use in deflection cantilever array-based protein detection
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In this project common linking and blocking procedures were examined for use in multiplexed deflection cantilever array-based detection of proteins. A human interferon gamma (INF-γ) enzyme-linked immunosorbent assay (ELISA) kit was used to evaluate the effectiveness of the linking and blocking...
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Fall 2024
The chloride intracellular channel (CLIC) isoform 5A was discovered in a complex with ezrin and actin in placenta microvilli. CLIC5A is also greatly enriched in kidney glomeruli and is essential for assembly of the ezrin/NHERF2/podocalyxin complex at the apical domain of glomerular podocyte foot...
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Synthesis, biological evaluation, and screening of 2,5-anhydro-D-mannitol derivatives towards selective targeting and imaging of GLUT5 transporter protein
DownloadFall 2022
The solute carrier (SLC) family of membrane proteins is responsible for the internalization of a variety of essential small molecule compounds such as amino acids, monosaccharides, neurotransmitters, vitamins, as well as many inorganic ions. In recent years, these proteins have been recognized as...
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Spring 2018
Intrinsically disordered regions (IDRs) in proteins lack stable three dimensional structure under physiological conditions. IDRs are prevalent in nature, functionally important, and difficult to characterize experimentally due to their unstructuredness. As a result, many computational methods...