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Skip to Search Results- 59Graduate and Postdoctoral Studies (GPS), Faculty of
- 59Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 18Chemistry, Department of
- 18Chemistry, Department of/Journal Articles (Chemistry)
- 8Pharmacy and Pharmaceutical Sciences, Faculty of
- 8Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy and Pharmaceutical Sciences)
- 59Thesis
- 19Article (Published)
- 7Article (Draft / Submitted)
- 2Conference/Workshop Poster
- 2Conference/Workshop Presentation
- 2Report
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Spring 2011
Third-generation optoelectronics, which utilize nanoscale materials, have received a considerable amount of attention in the chemical sciences and are poised to make a large impact in both fundamental research and real-world application. In order to make a contribution to the field, this thesis...
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Aquatic nanotoxicity testing: Insights at the biochemical, cellular, and whole animal levels
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Aquatic organisms are susceptible to waterborne nanoparticles and there is only limited understanding of the mechanisms by which these emerging contaminants affect biological processes. The unique properties of nanomaterials necessitate evaluation of standard toxicity testing techniques to...
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Spring 2019
Synthetic oligodeoxynucleotides containing unmethylated CpG motifs (CpG ODNs) are powerful stimulators of innate and adaptive immune responses, exerting their activity through the interaction with endolysosomal Toll-like receptor 9 (TLR9) expressed by antigen presenting cells (APCs). The strong...
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Cell-electronic Sensing of Cellular Responses and Toxicity Induced by Nanoparticles and Arsenic Species
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We demonstrate the development of a real-time cell analysis (RTCA) platform for studying nanoparticle- and arsenic-induced cytotoxicity with potential applications to risk assessment, environmental toxicity monitoring, and drug development. RTCA is an impedance-based in vitro detection system...
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Natural and anthropogenic inputs of arsenic and selenium to the environment in the Athabasca Bituminous Sands Region
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Industrial development of the Athabasca Bituminous Sands (ABS) in northern Alberta, Canada, has raised concerns that emissions of arsenic and selenium to the surrounding landscape and waterbodies have been increasing over time. To test this hypothesis, a comprehensive study of arsenic and...
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Fall 2009
Cytotoxic T lymphocytes (CTL) are differentiated CD8+ T cells that eliminate virally infected cells and tumor cells. CTL lyse target cells by at least two distinct mechanisms: degranulation of cytolytic molecules and cell surface expression of Fas ligand (FasL), which induces apoptosis of...
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Synthesis and screening of heterogeneous multimetallic nanoparticle catalysts for mono-, poly- and heteroaromatic hydrogenation activity under mild conditions
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Nanoparticle catalysts have shown to be advantageous over traditional catalysts for many reasons and active for a wide variety of reactions. This thesis describes an approach for the synthesis and screening of heterogeneous multimetallic nanoparticle catalysts for aromatic hydrogenation activity...