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Skip to Search Results- 4Field, Catherine J.
- 2Ametaj, Burim N.
- 2Dervishi, Elda
- 2Hailemariam, Dagnachew
- 2Proctor, Spencer D.
- 1Adam, Ibrahim S. Y.
- 32Graduate and Postdoctoral Studies (GPS), Faculty of
- 32Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 11Agricultural, Food and Nutritional Science, Department of
- 11Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Roy Berg Kinsella Research Ranch
- 2Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
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Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy
Download2009
Baracos, Vickie E., Xue, Hongyu, Sawyer, Michael B., Field, Catherine J
Infectious complications are a major cause of morbidity and mortality from dose-intensive cancer chemotherapy. In spite of the importance of intestinal bacteria translocation in these infections, information about the effect of high-dose chemotherapy on gut mucosal immunity is minimal. We studied...
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Small intestine early innate immunity response during intestinal colonization by Escherichia coli depends on its extra-intestinal virulence status
Download2016
Denamur, Erick, Tourret, Jérôme, Dion, Sara, Willing, Benjamin P., Wachtel, Sarah, Finlay, B. Brett, Dufour, Nicolas, Croxen, Matthew A.
Uropathogenic Escherichia coli (UPEC) strains live as commensals in the digestive tract of the host, but they can also initiate urinary tract infections. The aim of this work was to determine how a host detects the presence of a new UPEC strain in the digestive tract. Mice were orally challenged...
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Glutamine supplementation improves intestinal barrier function in a weaned piglet model of Escherichia coli infection
Download2011
Johnson, Ian R., Ewaschuk, Julia B., Murdoch, Gordon K., Field, Catherine J., Madsen, Karen L.
The weaning period is associated with an increased prevalence of gastrointestinal infection in many species. Glutamine (Gln) has been shown to improve intestinal barrier function and immune function in both in vivo and in vitro models. The objective of the present study was to determine the...
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Fall 2017
The inflammatory response is a complex biological process initiated following the recognition of noxious stimuli. It is composed of an elaborate cascade of both pro- and anti-inflammatory mediators, essential for effective defenses against infection, the removal of damaged cells, and the...
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Fall 2012
Teleosts rely on innate immunity to protect themselves from pathogens. Colony stimulating factor-1 (CSF-1) and its cognate receptor CSF-1R control survival, proliferation, differentiation and function of macrophages. Recently, a novel soluble form of CSF-1R (sCSF-1R) was identified in goldfish....
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Application of Next Generation Sequencing and Bioinformatic Approaches to the Study of Influenza Virus Strains and MiRNA Profiling in Liver Diseases
DownloadSpring 2016
Analysis and interpretation of next generation sequencing data has posed a significant challenge to researchers, especially to those who are not equipped with expertise in bioinformatics. In this thesis, I investigated three different biomedical questions using NGS and bioinformatic approaches,...
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Transcriptomic and epigenetic profiling of the lung of influenza-infected pigs: A comparison of different birth weight and Susceptibility groups
Download2015-09-22
Harding, John C.S., Foxcroft, George R., Gunvaldsen, Rayna E., Dyck, Michael K., Plastow, Graham S., Detmer, Susan E., Wilkinson, Jamie M., Dixon, Walter T.
Influenza viruses are a common cause of respiratory disease in swine. Infections range in severity from asymptomatic to causing significant morbidity. The main objective of this study was to compare lung transcriptomic and epigenetic responses to influenza infection in pigs from high or low birth...
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Dynamic Changes of Monocytes and Chemokine Pathway Signaling During Wound Healing Post-Burn Injury
DownloadSpring 2022
Background:There are over 11 million people hospitalized for burns annually according to the World Health Organization, resulting in painful skin scar contractures and restricted movements, as well as mental and physical stresses. Up to 70% of deep dermal injury result in hypertrophic scars,...
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Birth Weight, Intrauterine Growth Retardation and Fetal Susceptibility to Porcine Reproductive and Respiratory Syndrome Virus
Download2014
Ashley, C., Foxcroft, G., Plastow, G., Harding, J. C. S., Lunney, J. K., Ladinig, A.
The severity of porcine reproductive and respiratory syndrome was compared in pregnant gilts originating from high and low birth weight litters. One-hundred and eleven pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus on gestation day 85 (±1) were...
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Effect of providing a formula supplemented with long chain polyunsaturated fatty acids on immunity in full term neonates
Download2008
Robinson, Lindsay E., Field, Catherine J., Clandinin, M. Thomas, van Aerde, John E.
To determine the effect of feeding formula containing long-chain PUFA (LCP) on immune function, healthy term infants were randomised at age 2 weeks to either a standard term formula (Formula; n 14) or the same formula supplemented with the LCP 20 : 4n-6 and 22 : 6n-3 (Formula+LCP; n 16)....