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- 1Al-Saleh, Mohammed Ali
- 1Baldwin, Lesley
- 1Baron, Corey A
- 1Bergens, Steven H.
- 1Brett, Michael J.
- 49Graduate and Postdoctoral Studies (GPS), Faculty of
- 49Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 8Biomedical Engineering, Department of
- 8Biomedical Engineering, Department of/Journal Articles (Biomedical Engineering)
- 4Medicine and Dentistry, Faculty of
- 4Medicine and Dentistry, Faculty of/Journal Articles (Medicine and Dentistry)
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DETECTING CEREBRAL DEGENERATION IN ALS USING A MULTICENTRE APPLICATION OF 3D TEXTURE ANALYSIS
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Amyotrophic lateral sclerosis (ALS) is a highly heterogeneous disease in terms of its clinical presentation, progression, and detected pathology in the body. It is a multi-system degenerative disorder, though a diagnosis is made based on the presence of both upper motor neuron (UMN) and lower...
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Development and Application of Quantitative Gradient-Echo MRI Techniques for Assessment of Iron and Myelin in the Multiple Sclerosis Brain
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Multiple Sclerosis (MS) is a progressive autoimmune and neurodegenerative disease of the Central Nervous System that results in demyelination and neuronal/axonal loss. Along with clinical evaluation, Magnetic Resonance Imaging (MRI) is the gold standard modality for diagnosing and monitoring MS,...
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Fall 2013
Magnetic resonance imaging (MRI) is a valuable imaging modality and is commonplace in diagnosing, evaluating, and understanding the pathobiology of many neurological disorders. Current methods are helpful in the diagnosis of multiple sclerosis (MS) but fail to provide useful longitudinal...
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Fall 2022
Deformable registration of cardiac magnetic resonance imaging (MRI) is one of the crucial tasks in medical image analysis. It aims to find the unique transformation between images taken from the same scene at different times, from different views, and by different imaging modalities such as MRI...
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Fall 2014
Diffusion magnetic resonance imaging (dMRI) measures the diffusion (i.e. random molecular motion) of water. Since the motion of water is inhibited by cellular membranes, dMRI provides insight into the microstructural characteristics of the tissue. However, distinguishing between small anatomical...
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Fall 2016
Neurological disorders are among major causes of disability in Canada. In the diagnostic procedure, Magnetic Resonance Imaging (MRI) is commonly used as it is non-invasive and can produce dramatic contrast between different brain tissues. Brain tissue segmentation is a fundamental step in brain...
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Spring 2017
Pulses of ecdysone, a steroid hormone, play an integral role during insect development however, how these ecdysone pulses are regulated has been relatively unexplored. I have shown that the presence of nitric oxide (NO) within the larval prothoracic gland (PG), the principal source of larval...
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Fall 2020
Ecdysone, the primary steroid hormone in insects produced primarily in the prothoracic gland during larval development, is responsible for coordinating developmental transitions such as larval molts and metamorphosis during the Drosophila life-cycle. The ecdysone biosynthesis pathway, which...
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Fusion of Magnetic Resonance Imaging and Cone-Beam Computed Tomography: A New Approach to Diagnostic Imaging of Temporomandibular Joints.
DownloadSpring 2017
Aims: to develop a reliable and accurate method to co-register magnetic resonance imaging (MRI) and cone-beam computed tomography (CBCT) images for improved assessment of TMJ internal derangement in adolescents and adults, and to utilize this MRI-CBCT co-registration tool to quantify TMJ changes...