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Fall 2010
A 9.4 T magnetic resonance imaging (MRI) system was used to evaluate the response of a human tumour xenograft model to radiation therapy. The apparent diffusion coefficient (ADC) and the transverse relaxation time (T2) of human glioblastoma multiforme (GBM) tumour xenografts in NIH-iii nude mice...
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Fall 2011
Currently, the Cross Cancer Institute uses CT imaging in conjunction with the traditional Manchester system, which prescribes dose to a defined point, for cervix cancer brachytherapy. To take advantage of MRI for enhanced definition of soft tissue including the cancerous tissue itself, this...
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Spring 2012
A promising approach to the development of an integrated system for magnetic resonance imaging-guided radiotherapy involves the rigid coupling of a medical linear accelerator to a rotating biplanar magnet assembly. Through near real-time volumetric imaging during irradiation, this hybrid system...
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Magnetic resonance imaging based radiotherapy treatment planning: problems, solutions, and applications
DownloadFall 2010
Despite their unmatched soft-tissue contrast, Magnetic Resonance (MR) images suffer from wide-ranging image distortions; this has raised questions about their suitability as an imaging modality upon which to base conformal radiation therapy treatment plans. This thesis addresses image distortion...
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Spring 2010
A prototype system which has integrated a linear accelerator (linac) with a magnetic resonance imager (MRI) has been constructed at the Cross Cancer Institute. The real time operation of a linac-MRI system will require proper radio frequency (RF) shielding such that the MRI images can be acquired...