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Skip to Search Results- 2Elamy, Abdel-Halim H
- 1Achtymichuk, Karly A
- 1Akinwumi, Segun M
- 1Alotaibi, Ghazi S
- 1Ata, Nicole
- 1Baluch, Aliyah
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Spring 2023
Background: Unhealthy diet is a well-established risk factor for developing many physical health conditions in adolescents (e.g., obesity, type 2 diabetes). Evidence begins to emerge that unhealthy diet might also be implicated in the development of common mental disorders. While there is a...
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Helicobacter pylori infection in Arctic Indigenous communities: assessing the validity of infection status measures and estimating the effect of bacterial load on gastritis severity
DownloadSpring 2023
Helicobacter pylori (Hp) causes chronic inflammation of the stomach lining, also known as gastritis, in nearly all people with a persistent infection. Chronic inflammation of the stomach lining can lead to atrophy of stomach glands, a condition known as atrophic gastritis, believed to be the...
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IDENTIFYING ADOLESCENTS AT RISK OF DEVELOPING NEGATIVE OUTCOMES AFTER RECEIVING OPIOID ANALGESICS FOR CHRONIC NON-CANCER PAIN MANAGEMENT USING MACHINE LEARNING ALGORITHMS
DownloadSpring 2023
Canada's prescription opioid dispensing rates have increased since the early 21st century and this has contributed to an increase in opioid-related morbidity and mortality. Adolescents are one of the most vulnerable age groups when it comes to experiencing morbidity and mortality related to...
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Influenza Vaccination in Patients with Diabetes: Exploration of the Healthy User in Pharmacoepidemiology Studies
DownloadFall 2015
Pharmacoepidemiologic studies of preventive medications or therapies are prone to the healthy user bias, as patients who are prescribed and adhere to preventive medications/therapies are likely different than patients not receiving these medications in multiple aspects of their lives. These...
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Spring 2013
Immunogenicity of intramuscular influenza vaccine is suboptimal in organ transplant recipients although intradermal vaccine may be superior by targeting dermal dendritic cells to stimulate a response. 229 patients were randomized to IM or high-dose ID vaccine during the 2010-11 season. Pre- and...
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International Comparison of Time to Treatment Intensification and Rates of Complications in Metformin Monotherapy Treated Type 2 Diabetes Patients
DownloadFall 2018
Type 2 diabetes mellitus is a progressive disease which affects many people in Canada and the United States, and the prevalence of type 2 diabetes is only expected to increase in the future. Pharmacological interventions are a cornerstone of the management of type 2 diabetes as they help to...
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Spring 2010
These two studies investigate the immune responses of lung and kidney transplant recipients to the influenza vaccine. The study involving kidney transplant recipients developed a novel flow cytometry assay to measure cell-mediated immunity in response to influenza vaccination. The activation of...
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Mathematical Models and Inverse Algorithms for Childhood Infectious Diseases with Vaccination - Case Studies in Measles
DownloadFall 2014
Children are at a high risk of infection since they have not yet developed mature immunity. Childhood infectious diseases, such as measles, chicken pox and mumps, remain epidemic and endemic around the world. Yet, their dynamics are still not fully understood. SIR-type models have been proposed...
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Fall 2017
In recent years, narratives about various embellished and imaginary risks of vaccination have come under criticism because of their implications for the widespread acceptance of vaccines. Criticisms of these narratives often accompany assumptions that all mainstream health professionals accept,...
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Fall 2017
This thesis focuses on formulating and analyzing non linear models for microbial dynamics vis-a-vis human and environmental health. Firstly, we develop and investigate a stoichiometric organic matter decomposition model in a chemostat culture that incorporates the dynamics of grazers. This...