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Whose burden? A comprehensive approach to describing burden of disease by synthesizing evidence from diverse perspectives
DownloadFall 2018
Epidemiologists tasked with addressing public concerns about a specific health issue and developing effective public health strategies aimed at reducing related health risks must begin by describing the extent of the health threat in the target population. Typical approaches use quantitative...
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Spring 2015
Background: Diabetes and chronic kidney disease are two leading public health concerns. Patients with both diabetes and chronic kidney disease may be at elevated risk for suboptimal nutrient status due to diet restrictions, electrolyte and fluid imbalance, and altered metabolism. Objectives: The...
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Vitamin D supplementation and bone health in adults with diabetic nephropathy: The protocol for a randomised controlled trial
Download2014
Hoffmann, Michelle R., Jindal, Kailash, Senior, Peter A., Mager, Diana R., Jackson, Stephanie T.
Background Suboptimal vitamin D status is highly prevalent in Northern communities, particularly in those patients with chronic diseases such as diabetes and chronic renal disease. Emerging literature suggests that adherence to daily vitamin D supplementation may be an important factor...
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Vitamin D Supplementation and Bone Health in Adults with Diabetic Nephropathy: Preliminary Findings from a Randomized Controlled Trial
DownloadFall 2013
Vitamin D (vitD) is a nutrient of concern in Canada particularly for those with diabetes and chronic kidney disease (CKD). Participants (18-80y) with diabetes and CKD were randomized to receive either 50mcg/day (n=33) or 1,000mcg/month (n=30) vitD3 for 6-months. Variables studied included:...
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Vitamin D Status and Health-care Outcomes in an Ambulatory Population of Patients with Diabetes and Chronic Kidney disease: A Five-year Follow-up.
DownloadSpring 2018
Vitamin D (VitD) deficiency is a prevalent condition in Canada, especially in northern latitudes where sunlight exposure is limited. Elderly patients especially those with chronic conditions such as Diabetes Mellitus (DM) and Chronic Kidney Disease (CKD) have a higher risk of developing vitD...
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Using Narrative Inquiry to Elicit Diabetes Self-Care Experience in an Aboriginal Population.
Download2008
A narrative inquiry approach was used to explore the experience of Aboriginal people living with type 2 diabetes mellitus in a rural community. Narrative inquiry based on hermeneutic phenomenological philosophy was the methodology used to guide the research.A purposive sample of 4 persons of...
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Fall 2012
Individuals with type 2 diabetes (T2DM) have an increased risk of bladder cancer, relative to non-diabetic individuals. We aimed to investigate factors that may influence this association. Some reports suggest an association between the glucose-lowering drug pioglitazone and bladder cancer. Our...
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Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases
Download2012
Cabezas, Manuel C., Mamo, John C., Proctor, Spencer D., Botham, Kathleen M., Klop, Boudewijn
Postprandial hyperlipidemia with accumulation of remnant lipoproteins is a common metabolic disturbance associated with atherosclerosis and vascular dysfunction, particularly during chronic disease states such as obesity, the metabolic syndrome and, diabetes. Remnant lipoproteins become attached...
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Fall 2012
Cholera remains epidemic and endemic in the world, causing thousands of deaths annually in locations lacking adequate sanitation and water infrastructure. Yet its dynamics are still not fully understood. An indirectly transmitted infectious disease model, called an iSIR model, was recently...