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Skip to Search Results- 4Chakrabarti, Subhadeep
- 4Proctor, Spencer D.
- 4Wu, Jianping
- 3Field, Catherine J.
- 3Vine, Donna F.
- 2AlZahal, Ousama
- 52Graduate and Postdoctoral Studies (GPS), Faculty of
- 52Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 20Agricultural, Food and Nutritional Science, Department of
- 20Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Biological Sciences, Department of
- 3Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Role of Cytochrome P450 1B1 in Inflammation-induced Cardiac Hypertrophy
2023-05-17
ElKhatib, Mohammed, El-Kadi, Ayman
A great deal of research has demonstrated the involvement of cytochrome P450 (CYPs) enzymes and its metabolism of arachidonic acid (AA) in the modulation of cardiac hypertrophy (CH) pathogenesis. Multiple studies demonstrated that inflammation is a major contributor to CH and is known to...
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Fall 2023
12,13-dihydroxy-9z-octadecenoic acid (12,13-DiHOME) is a linoleic acid-derived cardiac metabolite produced in endotoxin-induced cardiomyopathy, correlating with myocardial dysfunction, inflammation, and mitochondrial damage. The contribution of 12,13-DiHOME to inflammation in the heart is...
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2005
van Houten, B., Patel, M., Chan, C. B., Orrenius, S. , Fariss, M. W.
Oxidative stress and mitochondrial oxidative damage have been implicated in the etiology of numerous common diseases. The critical mitochondrial events responsible for oxidative stress–mediated cell death (toxic oxidative stress), however, have yet to be defined. Several oxidative events...
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Small intestine early innate immunity response during intestinal colonization by Escherichia coli depends on its extra-intestinal virulence status
Download2016
Denamur, Erick, Tourret, Jérôme, Dion, Sara, Willing, Benjamin P., Wachtel, Sarah, Finlay, B. Brett, Dufour, Nicolas, Croxen, Matthew A.
Uropathogenic Escherichia coli (UPEC) strains live as commensals in the digestive tract of the host, but they can also initiate urinary tract infections. The aim of this work was to determine how a host detects the presence of a new UPEC strain in the digestive tract. Mice were orally challenged...
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T cell-mediated inflammation is stereotyped: mouse delayed-type hypersensitivity reaction and mouse T cell-mediated rejection of renal allografts share common molecular mechanismsT cell-mediated inflammation is stereotyped
DownloadFall 2011
Genome-wide gene expression analysis of diseases has revealed large-scale changes in the expression of thousands of genes (transcripts) representing biological processes. The processes that occur during T cell-mediated rejection (TCMR) of renal allografts in mice and humans have been previously...
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The analysis of cytokine regulation of macrophage antimicrobial responses of the goldfish (Carassius auratus L.)
DownloadFall 2011
Inflammation is a highly regulated immune response to tissue damage, infiltrating pathogens or both. Cells of the myeloid lineage such as macrophages are indispensable for the initiation, progression and resolution of inflammation. Macrophages possess an armamentarium of antimicrobial responses...