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Skip to Search Results- 21Graduate and Postdoctoral Studies (GPS), Faculty of
- 21Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 7Biological Sciences, Department of
- 7Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 3Biochemistry, Department of
- 3Biochemistry, Department of/Journal Articles (Biochemistry)
- 8Department of Chemistry
- 3Faculty of Pharmacy and Pharmaceutical Sciences
- 2Department of Chemical and Materials Engineering
- 2Department of Oncology
- 1Department of Agricultural, Food, and Nutritional Science
- 1Department of Biochemistry
- 4Vederas, John (Chemistry)
- 2Unsworth, Larry (Chemical and Materials Engineering)
- 1Derda, Ratmir
- 1Dr. Kaur, Kamaljit (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Kaur, Kamaljit (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
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2000
Sherwood, N.M., Craig, A.G., Park, M., Powell, J.F., Carolsfeld, J., Chang, J.P., Fischer, W.H., Rivier, J.E.
The evolution of GnRH and the role of multiple forms within the brain are examined. Three forms of GnRH were purified from the brain of Pacific herring (Clupea harengus pallasi) and characterized using Edman degradation and mass spectrometry. Two forms correspond with the known structures of...
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Primary structure of a novel gonadotropin-releasing hormone (GnRH) in the brain of a teleost, Pejerrey
Download2001
Somoza, G.M., Rivier, J.E., Fischer, W.H., Park, M.K., Chang, J.P., Craig, A.G., Montaner, A.D., Sherwood, N.M.
The neuropeptide GnRH is the major regulator of reproduction in vertebrates acting as a first signal from the hypothalamus to pituitary gonadotropes. Three GnRH molecular variants were detected in the brain of a fish, pejerrey (Odontesthes bonariensis), using chromatographic and immunological...
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Structural and functional analysis of transmembrane segment VI of the NHE1 isoform of the na+/H+ exchanger
Download2009-01-01
Tzeng, Jennifer, Lee, Brian L., Sykes, Brian D., Fliegel, Larry
The Na+/H+ exchanger isoform 1 is a ubiquitously expressed integral membrane protein. It resides on the plasma membrane of cells and regulates intracellular pH in mammals by extruding an intracellular H+ in exchange for one extracellular Na+. We characterized structural and functional aspects of...
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Structural and functional analysis of transmembrane XI of the NHE1 isoform of the na+/H+ exchanger
Download2009-01-01
Lee, Brian L., Li, Xiuju J., Liu, Yongsheng, Sykes, Brian D., Fliegel, Larry
The Na+/H+ exchanger isoform 1 is a ubiquitously expressed integral membrane protein that regulates intracellular pH in mammals by extruding an intracellular H+ in exchange for one extracellular Na+. We characterized structural and functional aspects of the critical transmembrane (TM) segment XI...
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Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the na+/H+ exchanger
Download2005-01-01
Slepkov, Emily R., Rainey, Jan K., Li, Xiuju J., Liu, Yonghsheng S., Cheng, Florence J., Lindhout, Darrin A., Sykes, Brian D., Fliegel, Larry
The Na+/H+ exchanger isoform 1 is a ubiquitously expressed integral membrane protein that regulates intracellular pH in mammals. We characterized the structural and functional aspects of the critical transmembrane (TM) segment IV. Each residue was mutated to cysteine in cysteine-less NHE1. TM IV...
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Spring 2016
The lipopeptides, tridecaptin A1, tridecaptin B1 and cerexin A1 were isolated from Paenibacillus terrae NRRL B-30644, Paenibacillus polymyxa NRRL B-30507 and Bacillus mycoides ATCC 21929, respectively. A combination of chemical synthesis, peptide derivatization, high performance liquid...
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Fall 2014
Paenibacillus polymyxa NRRL B-30509, Paenibacillus terrae NRRL B-30644 and P. polymyxa NRRL B-30507 were found to produce several bacteriocins and non-ribosomal peptides. All three strains produce tridecaptins, non-ribosomal lipopeptides antimicrobially active against food pathogen Campylobacter...
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Spring 2018
Acidocin B (AcdB), a bacteriocin from Lactobacillus acidophilus M46 that was initially reported to be a linear peptide, was purified and shown to be circular based on MALDI-TOF MS and MS/MS sequencing. MS analysis further revealed that AcdB is comprised of 58 amino acid residues, instead of 59...