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Skip to Search Results- 5Genome-wide association study
- 4Somatotropin
- 2Dairy cattle
- 2Epistasis
- 2Growth hormone releasing factor
- 2Heritability
- 1Department of Agricultural, Food, and Nutritional Science
- 1Department of Animal Science
- 1Department of Biological Sciences
- 1Department of Genetics
- 1Department of Physiology
- 1Medical Sciences- Laboratory Medicine and Pathology
- 1Coltman, David (Biological Sciences)
- 1Damaraju, Sambasivarao (Laboratory Medicine and Pathology)
- 1Davis, Corey (Biological Sciences)
- 1Lai, Raymond (Laboratory Medicine and Pathology)
- 1Paul Stothard, Department of Agricultural, Food and Nutritional Science
- 1Syrotuik, Daniel (Physical Education and Recreation)
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An investigation of endogenous ghrelin and growth hormone-releasing hormone following the consumption of two different relative doses of oral l-arginine
DownloadSpring 2011
Individuals consume the amino acid L-arginine (L-arg) to obtain an anabolic response. However, little is known concerning the mechanism for using an oral dose. The primary purpose of this investigation was to examine the influence of consuming two relative doses of oral L-arg on the growth...
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Genetic architecture of gene expression underlying variation in host response to porcine reproductive and respiratory syndrome virus infection
Download2017-04-10
Kommadath, Arun, Bao, Hua, Choi, Igseo, Reecy, James M., Koltes, James E., Fritz-Waters, Elyn, Eisley, Chris J., Grant, Jason R., Rowland, Robert R. R., Tuggle, Christopher K., Dekkers, Jack C. M., Lunney, Joan K., Guan, Le Luo, Stothard, Paul, Plastow, Graham S.
It has been shown that inter-individual variation in host response to porcine reproductive and respiratory syndrome (PRRS) has a heritable component, yet little is known about the underlying genetic architecture of gene expression in response to PRRS virus (PRRSV) infection. Here, we integrated...
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Fall 2013
Breast cancer is the most common cancer among women in the developed world. The disease results from the combined effects of genetic, environmental, reproductive and lifestyle risk factors. Germline DNA variations identified thus far by linkage and genome-wide association studies (GWASs) account...
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Improving Accuracy of Genomic Prediction for Economically Important Traits in Canadian Holstein Dairy Cattle
DownloadSpring 2017
Milk is a valuable source of energy, high quality protein, and several key minerals and vitamins for humans. Selection for milk production in dairy cattle was first based on phenotype and pedigree information and the knowledge of genetic parameters for the trait of interest. However, substantial...
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Looking beyond the standard genome-wide association study: Biologically-motivated methodological approaches to discover novel genetic variants associated with complex human traits and disease
DownloadFall 2018
The standard approach for testing associations between common single nucleotide genetic variants (referred to as single nucleotide polymorphisms or SNPs) and disease entails testing disease associations for each SNP in the genome individually. This “hypothesis-free” approach has identified...
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Spring 2016
Polar bears (Ursus maritimus) were among the first large mammals to be assessed for genetic variation in the wild, and they remain a common subject of genetics studies. Although recent advances in genotyping technology have allowed for more accurate determination of population structure and the...