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Skip to Search Results- 4Chakrabarti, Subhadeep
- 4Wu, Jianping
- 3Proctor, Spencer D.
- 2AlZahal, Ousama
- 2Curtis, Jonathan M.
- 2Davidge, Sandra T.
- 46Graduate and Postdoctoral Studies (GPS), Faculty of
- 46Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 20Agricultural, Food and Nutritional Science, Department of
- 20Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Medicine and Dentistry, Faculty of
- 2Pharmacy and Pharmaceutical Sciences, Faculty of
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2011
Boutin, Hervé, Crossman, David, Smigova, Alison, Drake, Caroline, Allan, Stuart M., Francis, Sheila, Gerhard, Alexander, Jones, Matthew S., Hinz, Rainer, Kassiou, Michael, Hopkins, Stephen J., Vail, Andy, Herholz, Karl, Tyrrell, Pippa J., Selvarajah, Johann R., Rothwell, Nancy J., Julyan, Peter, Georgiou, Rachel F., Brown, Gavin, Maroy, Renaud, Denes, Adam, Russell, James C., Proctor, Spencer D., McColl, Barry W., Prenant, Christian, Hulme, Sharon
Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity are associated with increased risk of stroke, which suggests that systemic inflammation may contribute to the development of stroke in humans. The hypothesis that systemic inflammation may induce brain...
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Butyrate-mediated genomic changes involved in the non-specific host defenses, matrix remodelling and the immune response in the rumen epithelium of cows afflicted with subacute ruminal acidosis
Download2013
Steele, Michael A., Greenwood, Sabrina L., Plaizier, Jan C., McBride, Brian W., Matthews, James C., Laarman, Anne H., AlZahal, Ousama, Dionissopoulos, Louis
Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by...
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Spring 2017
Characterization of Spinal Cord Microglia. Previous studies suggest that the functional response properties of activated brain microglia varied according to the brain region they were derived from, suggesting that these activation profiles are a function of their local environment. CNS microglia...
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Chemically defined diet alters the protective properties of fructo-oligosaccharides and isomalto-oligosaccharides in HLA-B27 transgenic rats
Download2014
Koleva, Petya, Ketabi, Ali, Dieleman, Levinus A., Gänzle, Michael G., Valcheva, Rosica
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but it remains unclear whether microbiota changes mediate their colitis-modulating effects. This study assessed intestinal microbiota and intestinal inflammation after feeding chemically defined...
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Spring 2011
Niemann-Pick Type C (NPC) disease is an autosomal recessive disorder that results in accumulation of unesterified cholesterol in late endosomes/lysosomes (LE/Ls), leading to progressive neurodegeneration and premature death. Microglia are resident immune cells of the central nervous system, which...
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CHROMATOGRAPHY APPROACHES FOR ANALYZING FRYING OILS AND ASSESSING THE ANTIOXIDATIVE ABILITY OF SITOSTEROL
DownloadFall 2013
The novel utility of sitosterol as an antioxidant in frying oils is explained mechanistically based on physical organic chemistry principles. The antioxidative effect of sitosterol is attributed to the conversion of sterol to steradiene by the 1, 2 elimination of water, which may be catalyzed by...
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Chronic Heart Failure: The Roles of the Tumor Necrosis Factor-Alpha Axis and Left-Atrial Structural and Functional Remodeling
DownloadFall 2014
Heart failure (HF) is a global epidemic, with a substantial burden on healthcare systems. Effective therapies have emerged for patients suffering from HF with reduced ejection fraction (HFREF), but not for those with preserved ejection fraction (HFPEF). Recently, systemic inflammation, driven by...
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Combined effect of pressure-assisted thermal processing and antioxidants on the retention of conjugated linoleic acid in milk
Download2015
Saldaña, Marleny D.A., Martinez-Monteagudo, Sergio I.
The effect of pressure-assisted thermal processing (PATP) in combination with seven synthetic antioxidants was evaluated on the retention of conjugated linoleic acid (CLA) in enriched milk. Milk rich in CLA was first saturated with oxygen, followed by the addition of either catechin, cysteine,...
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Comparative isolation of bacteria from inflamed sites to identify inflammation-tailored bacteria
DownloadSpring 2021
Microbial culture collections are fundamental to microbiology research. However, with the advent of next generation sequencing research, the generation and maintenance of comprehensive culture collections has become deprioritized. As such a need exists for the improved isolation of diverse...