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Skip to Search Results- 1Acedo, Jeella Z
- 1Afhami, Shima
- 1Cochrane, Stephen A.
- 1Dang, Jerry
- 1Dijk, Stephanie
- 1Doolin, Emma KA
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Application of antimicrobials for the elimination of Escherichia coli and Listeria monocytogenes in brine injected beef
DownloadFall 2013
The application of antimicrobials to a brine-injected raw beef roast for the elimination/inhibition of heat resistant Escherichia coli and Listeria monocytogenes was investigated. The choice of antimicrobials for use in brine injected beef was based on minimum bactericidal concentration in brine...
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Spring 2010
Although nanocrystalline silver is used commercially to treat burns and wounds, the mechanisms of action (MOA) for its activity are not clear. The purposes of this work were to determine if nanocrystalline silver has anti-inflammatory activity, determine physicochemical properties critical for...
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Effect of Antimicrobial Exposure on Clostridioides difficile (C. difficile) Colonization of the Infant Gut Microbiota in the Canadian Healthy Infant Longitudinal Development (CHILD) Birth Cohort
DownloadSpring 2020
Introduction: Antimicrobial exposure in early life has been associated with gut microbiota dysbiosis and development of allergic diseases in childhood. In adults and older children, C. difficile is the major pathogen responsible for antibiotic-induced diarrhea but the effect of colonization with...
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Fall 2020
Introduction By 2030, 1/100 Canadians are predicted to be diagnosed with inflammatory bowel diseases (IBD); approximately 25% of cases are diagnosed in children. IBD include Crohn disease (CD) and ulcerative colitis (UC), and manifest with chronic gastrointestinal inflammation. Pathogenesis...
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Investigating early life microbial and host transcriptomic dynamics in the bovine gastrointestinal tract
DownloadSpring 2019
There is increasing concern surrounding the ability of livestock industries to meet the needs of the rising global population. The gastrointestinal microbiota of ruminants plays a critical role in feed degradation, host energy supply, but is also a substantial source of anthropogenic greenhouse...
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Fall 2021
Spinal cord injury (SCI) not only leads to motor and sensory dysfunction, but just as debilitating are secondary consequences of SCI such as bowel disorders, neuroinflammation, immune suppression, pain and psychiatric disorders. In this thesis, I explore multiple aspects of recovery after SCI in...
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Mechanisms of Neonatal Intestinal Failure-Associated Liver Disease: Exploring the Gut-Liver Axis
DownloadSpring 2018
Neonates with intestinal failure (IF), who must rely on parenteral nutrition (PN) for growth and maintenance of health, are at risk for intestinal failure-associated liver disease (IFALD). In neonates, short bowel syndrome (SBS) as a result of intestinal resection is the most common cause of IF....
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Modulation of the uptake and toxicity of PFOA by Polystyrene and Titanium dioxide nanoparticles in Pacific oysters (Magallana gigas) and Daphnia (Daphnia magna)
DownloadFall 2023
Nanomaterial toxicity is a major concern in today’s world. The benefits of nanoparticle use have led to the production of various kinds of nanomaterials including a high volume of nanoplastics, TiO2 nanoparticles, and CeO nanoparticles. Different nanomaterials are shown to be a suitable vector...
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Spring 2017
Mussels can obtain strong underwater attachment to virtually all kinds of surfaces including rocks, metals, wood structures, polymers and concretes by secreting mussel foot proteins to form byssus. Great efforts have been dedicated to understanding this behavior and it is found that an catecholic...
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Non digestible carbohydrates in the diet determine toxicity of irinotecan (CPT-11)/5-fluorouracil in rats independently of β-glucuronidase activity in intestinal lumen
DownloadFall 2012
Aim of this study was to assess effects of non-digestible carbohydrates on the pathobiology of mucosal injury after chemotherapy. Rats bearing colon tumor (n=6/diet) were fed diets including 8% (w/w) as either cellulose, inulin, fructo-oligosaccharide (OligoF), 50:50 (w/w) inulin and oligoF...