Search
Skip to Search Results- 2Veldhoen, Richard
- 1Abazari Torqabeh, Alireza
- 1Abdualmjid,Reem J
- 1Abdurrahim, Amna E.
- 1Araya, Luam Ellen
- 1Baghdasarian, Argishti
-
Spring 2023
Hyaline cartilage is a strong and flexible connective tissue found throughout the human body. It provides important structural and functional support for the nose, ribs, larynx, and trachea. Due to the avascular nature of the hyaline cartilage, its defects or lesions are non-regeneratable and...
-
Spring 2012
In Pulmonary Arterial Hypertension (PAH), pro-constrictive, pro-proliferative and anti-apoptotic diatheses converge to produce contraction and excessive proliferation of pulmonary artery smooth muscle cells (PASMC), a hallmark of PAH-vascular remodeling. The increased afterload causes right...
-
An examination of parent-child dyadic interaction and the impact of a parent-training program designed to support the language development of toddlers diagnosed with autism spectrum disorder (ASD)
DownloadFall 2010
Parents can effectively facilitate positive child behaviour change (Kaiser & Hancock, 2003). Their inclusion as interventionists is an essential component of autism intervention (NRC, 2001) and represents a natural step toward consistent early intervention. However, what constitutes effective...
-
An investigation of aminoglutethimide cytotoxicity and its role in activation of cell death signaling pathways
DownloadFall 2013
Aminoglutethimide (AG), a drug used for the treatment of breast and ovarian cancers, is known to cause toxicities such as agranulocytosis. To investigate its toxicity mechanisms, we have used quantitative proteomic analysis to gain insight into the proteome of Human Leukemia 60 (HL-60) treated...
-
Anthocyanins and Gingerols Exhibit Synergism in their Anticancer and Antioxidant Effects in Vitro
DownloadFall 2022
Anthocyanins and gingerols are naturally occurring phenolic compounds abundant in berries and ginger, respectively. They have been reported to induce antioxidant effects, inhibit the growth of different cancer cell lines, and stimulate apoptosis by modulating different cellular signal pathways....
-
Fall 2012
Taxane chemotherapy is widely used in the treatment of breast cancer. Despite its widespread clinical use, the molecular mechanisms of paclitaxel induced apoptosis remain unclear. Our laboratory has identified an important role for the BH3-only protein, BAD, in the paclitaxel induced cell death...
-
Bacterial stimulation of lipid vesicle production in green microalga Dunaliella tertiolecta
DownloadFall 2019
Algae and bacteria form complex interactions through the exchange of bioactive molecules and nutrients. A wide range of phenotypes, and often their very survival, are influenced by these chemically mediated relationships, shaping the ecology and diversity of marine communities. Here we sought to...
-
Fall 2009
Recent advances in the fundamental theories in cryobiology using thermodynamic principles have created new opportunities for innovative methodologies in cryobiology. This thesis tested the hypothesis that calculated indicators of the two-factor hypothesis of cryoinjury, depending on cellular...
-
Spring 2014
The introduction of WNV into North America in 1999 was followed by rapid spread throughout the continent. Today, WNV is an endemic pathogen in the west, with thousands of cases of severe infection reported annually. In addition to traditional vaccine research, there is an urgent need to...