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- 20Interactions
- 12Affinity
- 10Electrospray ionization mass spectrometry
- 7Proteins
- 4Lipids
- 21Graduate and Postdoctoral Studies (GPS), Faculty of
- 21Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 20Chemistry, Department of
- 20Chemistry, Department of/Journal Articles (Chemistry)
- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Screening carbohydrate libraries for protein interactions using the direct ESI-MS assay: Applications to libraries of unknown concentration
Download2014
El-Hawiet, Amr, Klassen, John S., Kitova, Elena N.
A semiquantitative electrospray ionization mass spectrometry (ESI-MS) binding assay suitable for analyzing mixtures of oligosaccharides, at unknown concentrations, for interactions with target proteins is described. The assay relies on the differences in the ratio of the relative abundances of...
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Spring 2014
Two studies examined the effects of 3 commercial cat diets varying in glycemic index (GI) based on ingredient composition and starch content (34.1, 29.5, and 23.6% NFE for high, medium, and low GI, respectively) on metabolizable energy (ME), indirect calorimetry and blood measurements. In Study...
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Structure and stability of carbohydrate-lipid interactions: Methylmannose polysaccharide-fatty acid complexes
Download2016
Klassen, John S., Siuda, Iwona, Renaud, Justin, Tieleman, D. Peter, Kitova, Elena N., Liu, Lan, Mayer, Paul M., Richards, Michele R., Lowary, Todd L.
We report a detailed study of the structure and stability of carbohydrate–lipid interactions. Complexes of a methylmannose polysaccharide (MMP) derivative and fatty acids (FAs) served as model systems. The dependence of solution affinities and gas-phase dissociation activation energies (Ea) on FA...
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Structure and stability of carbohydrate-lipid interactions: Methylmannose polysaccharide-fatty acid complexes
Download2016
Mayer, Paul M., Richards, Michele R., Lowary, Todd L., Renaud, Justin, Klassen, John S., Tieleman, D. Peter, Kitova, Elena N., Liu, Lan, Siuda, Iwona
We report a detailed study of the structure and stability of carbohydrate–lipid interactions. Complexes of a methylmannose polysaccharide (MMP) derivative and fatty acids (FAs) served as model systems. The dependence of solution affinities and gas-phase dissociation activation energies (Ea) on FA...
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Studies Towards Understanding the Biosynthesis of Methyl Phosphoramidates found in Campylobacter jejuni
DownloadFall 2016
The human pathogen Campylobacter jejuni is the leading cause of food-borne gastroenteritis, causing more foodborne illnesses than Salmonella, Shigella, and Listeria combined. Of the approximate 5.3 million people infected every year in North America alone, approximately 1/1000 will develop the...
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Fall 2013
Solubility of glucose and lactose in subcritical water (SCW) was first determined at different pressures and temperatures. Sugar solubility increased with temperature but decreased with an increase in pressure. Then, carbohydrates and phenolics were extracted from lentil husk and cotyledon using...
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The Design, Synthesis and Evaluation of Multivalent Heterobifunctional Ligands Specific for Shiga Toxin 1 and Shiga Toxin 2
DownloadSpring 2014
Hemolytic uremic syndrome (HUS) is a potential life-threatening condition caused by infection with Shiga toxin-producing Escherichia coli O157:H7. There are two major types of Shiga toxins, namely, Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2), of which, Stx2 is clinically most closely associated...
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1992
Price, M. A., Berg, R. T., Shahin, K. A.
Data from carcasses of 210 cattle (119 bulls and 91 steers) from 4 breed types, serially slaughtered from = 200-008kg kg liveweight were used to test the hypothesis of similar gender dimorphism among breeds in relation to carcass bone growth and distribution. Relative to total bone weight, breed...
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Spring 2010
Heterogeneity of surfaces is often included in mathematical treatments of colloid transport and deposition as an afterthought, if at all. Most previous models of colloid transport and deposition have employed idealizations and simplifications such as assuming smooth collector surfaces with...