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Skip to Search Results- 1Al Onazi, Mona Moraybed
- 1Alyenbaawi, Hadeel Eb
- 1Barber, Quinn
- 1Bernier, Ashlyn
- 1Champion, Claudine C.
- 1Chaurasiya, Shyambabu
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Fall 2017
For cancer research, a powerful imaging modality for both preclinical (where the focus is on imaging small animals) and clinical (where the focus is on imaging human subjects) applications should be inexpensive, portable, noninvasive, safe, and capable of measuring a myriad of information....
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Drug Resistance in Breast Cancer: Characterization of Rationally Designed Paclitaxel Analogs in Model Systems
DownloadFall 2013
Breast cancer is a leading cause of cancer related deaths among women in the developed world. Treatment options for breast cancer include taxanes, which mediate cytotoxic effects by inducing microtubule polymerization which impedes cell division. Taxane resistant breast cancer is a mounting...
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Effect of Adenovirus-mediated Decorin Gene Therapy on Fibrotic Remodeling in Tissue-engineered Skin
DownloadFall 2016
Background: Hypertrophic scar (HTS) is a fibroproliferative disorder of the skin that results in the development of painful, red, raised scar lesions. Transforming growth factor beta 1 (TGF-β1) has been implicated as a key driver of this disorder. Primarily, these effects include an increased...
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Epidemiological Characteristics and Ecological Investigation of the 2009 Influenza Pandemic
DownloadFall 2014
Influenza pandemic occurs when a novel influenza virus subtype for which humans do not have sufficient immunity emerges and spreads quickly from person-to-person worldwide. Influenza pandemics result in serious consequences on human health and economy. In April 2009, the World Health Organization...
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Evaluation of Hypoxia Induced Regulation of Nucleoside and Amino Acid Membrane Transporters in Breast Cancer
DownloadSpring 2020
Positron Emission Tomography (PET) utilizes radioactively tagged molecules to identify cancerous tissue. In most cases, membrane transporters control entry of these molecules into human cancer cells. Hypoxia-inducible factor (HIF)-1 is the master homeostatic regulator during hypoxia in human...
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Ganglioside Increases Metastatic Potential and Susceptibility of Prostate Cancer to Gene Therapy in vitro
DownloadFall 2009
Prostate cancer (CaP) is the 2nd most common cancer in North American men. Tumour management strategies are appropriate for early stage disease, but advanced disease has a poor prognosis and requires prompt treatment. Therefore, research into delay of tumour progression and efficacious treatment...
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Giving Voice to the Unheard: Perceptions, Practices & Beliefs About Breast Cancer and Screening Among Ethnic Minority Women From the MENA (Middle East & North Africa) Region in Edmonton, Alberta.
DownloadFall 2019
Breast cancer is one of the major causes of death among women in Canada and globally. In Canada, screening has been found to be successful in decreasing morbidity and mortality (Canadian Cancer Society, 2015). Use of breast cancer screening services by immigrant women however is limited...
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Fall 2011
Breast cancer is the second leading cause of cancer death in Canadian women. In these patients, mortality is due to metastasis of cancer cells from the breast to distant organs, resulting in impairment of function. To metastasize, cells must move through the stroma of the breast, enter the...
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Profiling and Identification of Small Non-coding RNAs as Prognostic Markers for Breast Cancer
DownloadFall 2016
Breast cancer (BC) continues to be one of the leading causes of cancer related death among women. Despite continuous progress in screening, diagnosis and treatment of BC, a subset of patients experience recurrence and/or death. Optimal management of BC has remained a challenge due to these...
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Quantitative and Qualitative Content Analysis of Breast Cancer, Heart Disease, and Stroke Media Messages from Local Canadian Media
DownloadFall 2014
This study examined media coverage of breast cancer (N=145) and heart disease and stroke (N=39) news articles, videos, advertisements, and images in a local Canadian context through quantitative and thematic content analyses. Statistical analysis (Cramer’s V) revealed significant differences in...