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Skip to Search Results- 238Chemistry, Department of
- 227Chemistry, Department of/Journal Articles (Chemistry)
- 11Chemistry, Department of/Research Data and Materials (Chemistry)
- 1Human Ecology, Department of
- 1Human Ecology, Department of/Journal Articles (Human Ecology)
- 1Electrical and Computer Engineering, Department of
- 69Klassen, John S.
- 54Serpe, Michael J.
- 52Kitova, Elena N.
- 18Michaelis, V.K.
- 17Gao, Yongfeng
- 14Loppnow, Glen R.
- 20Electrospray ionization mass spectrometry
- 14Etalons
- 13SSNMR
- 12Affinity
- 12Stimuli-Responsive Polymers
- 11Complexes
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Screening oligosaccharide libraries against lectins using the proxy protein electrospray ionization mass spectrometry assay
Download2016
Privé, Gilbert G., Ng, Kenneth K. S., Xiong, Zi Jian, Klassen, John S., Kitova, Elena N., Fan, Xuxin, Li, Jun, Zou, Chunxia, Eugenio, Luiz, Cairo, Christopher W.
An electrospray ionization mass spectrometry (ESI-MS) assay for screening carbohydrate libraries against lectins is described. The assay is based on the proxy protein ESI-MS method, which combines direct ESI-MS protein–ligand binding measurements and competitive protein binding, to simultaneously...
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2018-11-16
Guo, Tianlin, Heon-Roberts, Rachel, Zou, Chunxia, Zheng, Ruixiang, Pshezhetsky, Alexey V, Cairo, Christopher W.
Inhibitors of human neuraminidase enzymes (NEU) are recognized as important tools for the study of the biological functions of NEU and will be potent tools for elucidating the role of these enzymes in regulating the repertoire of cellular glycans. Here we report the discovery of selective...
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2018-01-05
Guo, Tianlin, Datwyler, Philipp, Demina, Ekaterina, Richards, Michele R, Ge, Peng, Zou, Chunxia, Zheng, Ruixiang Blake, Fougerat, Anne, Pshezhetsky, Alexey V, Ernst, Beat, Cairo, Christopher W.
Human neuraminidases (NEU) are associated with human diseases including cancer, atherosclerosis, and diabetes. To obtain small molecule inhibitors as research tools for the study of their biological functions, we designed a library of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues...
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2012
Cutler, J. E., Dziadek, S., Bundle, D. R., Cartmell, J., Xin, H., Bailey, J. J.
Our research on pathogenesis of disseminated candidiasis led to the discovery that antibodies specific for Candida albicans cell surface b-1, 2–mannotriose [b-(Man)3] protect mice. A 14 mer peptide Fba, which derived from the N-terminal portion of the C. albicans cytosolic/cell surface protein...
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SEM Images of Block Copolymer Templated Patterns from PS-b-P2VP on Silicon with Platinum for Testing with ADAblock
SEM Images of Block Copolymer Templated Patterns from PS-b-P2VP on Silicon with Platinum for Testing with ADAblock
Download2014-07-05
Scanning electron microscope (SEM) images of patterns derived from polystyrene-block-poly(2-vinylpyridine), where the poly(2-vinylpyridine) domains replaced with platinum metal. All samples were annealed for 20 minutes at 200 degrees celsius. Polymers used include PS(23.6k)-b-P2VP(10.4k),...
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Sequential and controlled release of small molecules from poly(N-isopropylacrylamide) microgel-based reservoir devices
Download2016
Serpe, Michael J., Wong, Ka Y., Ahiabu, Andrews, Gao, Yongfeng
Systems composed of a poly(N-isopropylacrylamide)-co-acrylic acid (pNIPAm-co-AAc) microgels (AAc-MG) and poly(N-isopropylacrylamide-3-(acrylamido)phenylboronic acid) (pNIPAm-co-APBA) microgels (APBA-MG) were used to sequentially release small molecules to a system in a controlled and triggered...
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Siglecs induce tolerance to cell surface antigens by BIM-dependent deletion of the antigen-reactive B cells
2014
Paulson, J. C. , Macauley, M. S.
Infusion of blood cells from a donor can induce humoral tolerance in a recipient and increase the probability of successful organ transplant, a clinical method defined as donor-specific transfusion (DST). Despite the clinical success of DST, the immunological mechanisms by which blood cells...
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2019-01-01
Thiessen, A.N., Ha, M., Hooper, R.W., Yu, H., Oliynyk, A.O., Veinot, J.G.C., Michaelis, V.K.
Silicon nanoparticles (SiNPs) are biologically compatible, metal-free quantum dots that exhibit size and surface tailorable photoluminescence. The nanostructure of these materials influences their optical, chemical, and material properties and hence plays an important role in their...
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Simple Aqueous Preparation of High Activity and Stability NiFe Hydrous Oxide Catalysts for Water Oxidation
Download2016-10-27
Wang, Chao, Moghaddam, Reza B., Brett, Michael J., Bergens, Steven H.
A series of Ni1–xFex hydrous oxide nanoparticles (HO-nps, x = 0–0.5, 1) were prepared by stirring 0.1 M KOH solutions of NiCl2 and FeCl2 under air at room temperature. The resulting HO-nps can be used directly, or washed and isolated without loss of activity. The Ni1–xFex HO-nps are outstandingly...
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2016
Li, Xue, Serpe, Michael J., Gao, Yongfeng
Poly (N-isopropylacrylamide) (pNIPAm)-based hydrogels and hydrogel particles (microgels) have been extensively studied since their discovery a number of decades ago. While their utility seems to have no limit, this feature article is focused on their development and application for sensing small...