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Skip to Search Results- 2Jutras, Jean-David
- 2Yip, Eugene
- 1Abdou, Ismail
- 1Adamia, Sophia
- 1Alaee, Mahsa
- 1Anderson, Danielle L.
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J-Coupling Effects on Quantification of the 1.3 ppm Lipid Methylene Resonance with In-Vivo Magnetic Resonance Spectroscopy at 3 T
DownloadFall 2015
Quantification of 1.3 ppm lipid methylene protons by proton magnetic resonance spectroscopy has been shown to be relevant to a number of diseases. Additionally, T2 estimation of 1.3 ppm methylene protons has been used to grade the metastatic potential of colon tumours. J-coupling...
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Fall 2015
The repair of damaged DNA is critically important for maintaining a stable cellular environment to ensure proper and high fidelity segregation and transmission of genetic information from one generation to the next. DNA can be subjected to many forms of DNA damage that are handled by dedicated...
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Fall 2016
The integration of clinical linear accelerators (linacs) with magnetic resonance imaging (MRI) systems represent the next generation of image guidance technologies in radiotherapy. Linac-MR systems have several potential advantages over the current X-ray based state-of-the-art image guidance...
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Fall 2011
The integration of a clinical linear accelerator (linac) with a magnetic resonance imager (MRI) will offer real time images during treatment, making tumor tracking possible. One of the challenges of the integration is removing any mutual interference between the two systems. Methods of removing...
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Fall 2012
Malignant gliomas (MG) are the most common and aggressive brain cancers. FABP7 is an intracellular lipid trafficking molecule whose expression correlates with reduced MG patient survival. FABP7 has been shown to increase the migratory behaviour of MG cells. Moreover, the migratory behaviour of...
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Metal Artifact Reduction in Computed Tomographic (CT) Images for Radiotherapy Treatment Planning
DownloadSpring 2014
High density/high atomic number metallic objects create shading and streaking metal artifacts in the CT image that can cause inaccurate delineation of anatomical structures or inaccurate radiation dose calculation. We developed techniques for reducing metal artifacts in both megavoltage CT...
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Microtubules and Energy Metabolism: Targets for Standard, Combination, and Novel Therapeutic Interventions and Monitoring of Cancer
DownloadSpring 2016
The challenge of understanding and treating cancer has proven to be exceedingly complex. At this juncture, understanding cancer from the perspective of a breakdown of a complex cooperative system using a biophysical analysis may aid in improved treatments and prevention of this disease. In any...
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Spring 2011
The Reelin-Disabled-1 (Dab1) signaling pathway plays a key role in regulating neuronal positioning and synaptic plasticity. Binding of Reelin to its receptors induces tyrosine phosphorylation of the intracellular adaptor protein Dab1. Tyrosine-phosphorylated Dab1 not only rapidly transmits the...