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Spring 2012

Lakusta, Bonnie J

The association between stimulant drug use and the presence of a psychotic disorder raises questions about causation. Substance-induced psychosis may differ etiologically from schizophrenia despite similar phenotypic presentation. It is possible that stimulant drug users who develop symptoms of...

Spring 2017

Rossolatos, David

Cannabis use is a known risk factor for the development of psychotic disorders. Clinical and preclinical genetic studies provide growing evidence that genes related to dopamine signalling and neuroprotection, like COMT, are implicated in the cannabis-psychosis association. Considering the burden...

Fall 2012

Sidhu, Gagan

Functional Magnetic Resonance Imaging (fMRI) measures the dynamic activity of each voxel of a brain. This dissertation addresses the challenge of learning a diagnostic classifier that uses a subject’s fMRI data to distinguish subjects with neuropsychiatric disorders from healthy controls. fMRI...

Fall 2020

Paul, Animesh Kumar

While it is very difficult to diagnose/prognosis psychiatric disorders reliably, especially in early course, such early diagnosis/prognosis is critical for producing an effective treatment. This necessity has motivated many researchers to apply machine learning approaches to high-dimensional...

Fall 2010

Bresee, Lauren

Objective - To assess the relationship between schizophrenia and cardiovascular disease by evaluating metabolic risk associated with treatment for schizophrenia, prevalence of cardiovascular risk factors (CV-RF) and disease (CV-D), and health care utilization in people with schizophrenia...

Spring 2016

Paylor, John W

Schizophrenia (SCZ) is a psychiatric disorder that, despite a high prevalence (1% population worldwide) and burden of disease (1% global burden of disease), has a poorly understood etiology. While symptoms of SCZ typically manifest during adolescence and early adulthood, there is a substantial...

Fall 2023

Paylor, John W

Perineuronal nets (PNNs) are organized components of the extracellular matrix that surround mature neurons of the central nervous system (CNS). These structures have neuroprotective properties for host cells, provide structural and functional stability, and have been implicated in brain functions...

Spring 2012

Al-Ghamdi,Mohammad S

Stimulus-elicited (phasic) skin conductance responses (SCRs) to indifferent stimuli have often been employed to examine abnormalities in orienting (allocation of attention) in studies of schizophrenia. Most previous studies have examined phasic activity only during habituation paradigms....

1998

Mickelow, Garry Stephen

1974

Shen, Francis.