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Skip to Search Results- 14Young, T. Kue
- 4Hegele, Robert A.
- 4Nykiforuk, Candace I.J.
- 2Ban, Matthew R.
- 2Bjerregaard, Peter
- 2Bruce, Sharon
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1999-08-04
Hegele, Robert A., Anderson, Carol, Young, T. Kue, Connelly, Philip W.
"The GNB3 825T allele encodes a product that has enhanced activation of heterotrimeric G proteins in vitro and could play a role in adipogenesis. We therefore evaluated the possibility that the GNB3 825T allele was associated with obesity in a sample of 213 healthy Canadian Inuit. We found that...
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2001-06-01
Hegele, Robert A., Huff, Murray W., Young, T. Kue
"We discovered that rare mutations in LMNA, which encodes lamins A and C, underlie autosomal dominant Dunnigan-type familial partial lipodystrophy. Because familial partial lipodystrophy is an extreme example of genetically disturbed adipocyte differentiation, it is possible that common variation...
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Promoter Polymorphism in PCK1 (Phosphoenolpyruvate Carboxykinase Gene) Associated with Type 2 Diabetes Mellitus
Download2004-02-01
Cao, Henian, van der Veer, Eric, Ban, Matthew R., Hanley, Anthony J.G., Zinman, Bernard, Harris, S. B., Young, T. Kue, Pickering, J. Geoffrey, Hegele, Robert A.
"We sequenced the promoter and coding regions of PCK1 encoding cytosolic phosphoenolpyruvate carboxykinase from genomic DNA of subjects with type 2 diabetes mellitus (DM). We found nine single nucleotide polymorphisms (SNPs) that were present with varying allele frequencies and pairwise linkage...
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2007-11-14
Tremblay, Mark S., Shephard, Roy J., Brawley, Lawrence R., Cameron, Christine, Craig, Cora Lynn, Duggan, Mary, Esliger, Dale W., Hearst, William, Hicks, Audrey, Janssen, Ian, Katzmarzyk, Peter T., Latimer, Amy E., Martin Ginis, Kathleen A., McGuire, Ashlee, Paterson, Donald H., Sharratt, Michael, Spence, John C., Timmons, Brian, Warburton, Darren, Young, T. Kue, Zehr, Lori
"This article summarizes the main findings from the papers included in this journal supplement. It consolidates the evidence currently available to inform and advance the development of physical activity guidelines for Canadians, and it highlights the specific needs of various population...
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Prevalence of Obesity and Its Metabolic Correlates Among the Circumpolar Inuit in 3 Countries
Download2007
Young, T. Kue, Bjerregaard, Peter, Dewailly, Eric, Risica, Patricia M., Jørgensen, Marit E., Ebbesson, Sven E. O.
"Objectives: We investigated the prevalence of obesity and the metabolic correlates of different levels of body mass index (BMI) and waist circumference among the Inuit in 3 countries. Methods: Data from 4 surveys of Inuit in Canada, Greenland, and Alaska conducted during 1990–2001 were pooled,...
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2007-11-14
Young, T. Kue, Katzmarzyk, Peter T.
"This paper summarizes available information on patterns of physical activity, their determinants and consequences, and the results of various interventions designed to increase the physical activity of Aboriginal peoples in Canada and the United States. There is a paucity of national data on...
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Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample
Download2008-03-13
Al-Attar, Salam A., Pollex, Rebecca L., Ban, Matthew R., Young, T. Kue, Bjerregaard, Peter, Anand, Sonia S., Yusuf, Salim, Zinman, Bernard, Harris, Stewart B., Hanley, Anthony J. G., Connelly, Philip W., Huff, Murray W., Hegele, Robert A.
"Background: The rs9939609 T>A single-nucleotide polymorphism (SNP) in the FTO gene has previously been found to be associated with obesity in European Caucasian samples. The objective of this study is to examine whether this association extends to metabolic syndrome (MetS) and applies in...
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2009-05-28
Fergenbaum, Jennifer H., Bruce, Sharon, Lou, Wendy, Hanley, Anthony J.G., Greenwood, Carol, Young, T. Kue
"The association between obesity, other cardiovascular risk factors, and cognitive function in a Canadian First Nations population was investigated using a cross‐sectional design. Eligible individuals were aged ≥18 years, without a history of stroke, nonpregnant, with First Nations status, and...
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2009
Lix, Lisa M., Bruce, Sharon, Sarkar, Joykrishna, Young, T. Kue
"Background: In Canada, the prevalence of behavioural risk factors and chronic conditions differs for Aboriginal and non-Aboriginal populations, but little research has examined changes over time. This study compares several major risk factors and chronic conditions in Aboriginal and...
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Emerging obesity among preschool-aged Canadian Inuit children: results from the Nunavut Inuit Child Health Survey
Download2010-04-26
Galloway, Tracey, Young, T. Kue, Egeland, Grace M.
"Objectives: The study goal was to evaluate the growth status of preschool-age Canadian Inuit children. Study design: As part of a larger study of population health across the Canadian High Arctic, the International Polar Year Inuit Health Survey collected growth and nutrition data on 388...