Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

• Author(s) / Creator(s)

  • Al-Attar, Salam A.
  • Pollex, Rebecca L.
  • Ban, Matthew R.
  • Young, T. Kue
  • Bjerregaard, Peter
  • Anand, Sonia S.
  • Yusuf, Salim
  • Zinman, Bernard
  • Harris, Stewart B.
  • Hanley, Anthony J. G.
  • Connelly, Philip W.
  • Huff, Murray W.
  • Hegele, Robert A.

• "Background: The rs9939609 T>A single-nucleotide polymorphism (SNP) in the FTO gene has previously been found to be associated with obesity in European Caucasian samples. The objective of this study is to examine whether this association extends to metabolic syndrome (MetS) and applies in non-Caucasian samples. Methods: The FTO rs9939609 SNP was genotyped in 2121 subjects from four different non-Caucasian geographical ancestries. Subjects were classified for the presence or absence of MetS according to the International Diabetes Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel (NCEP ATP) III definitions." (as cited in abstract)

• Date created

  2008-03-13

• Subjects / Keywords

  • Metabolic syndrome
  • Obesity
  • Comparative studies
  • Ontario
  • Greenland

• Type of Item

  Article (Published)

• DOI

  https://doi.org/10.7939/r3-pck1-7z16

• License

  Attribution 4.0 International