Promoter Polymorphism in PCK1 (Phosphoenolpyruvate Carboxykinase Gene) Associated with Type 2 Diabetes Mellitus

• Author(s) / Creator(s)

  • Cao, Henian
  • van der Veer, Eric
  • Ban, Matthew R.
  • Hanley, Anthony J.G.
  • Zinman, Bernard
  • Harris, S. B.
  • Young, T. Kue
  • Pickering, J. Geoffrey
  • Hegele, Robert A.

• "We sequenced the promoter and coding regions of PCK1 encoding cytosolic phosphoenolpyruvate carboxykinase from genomic DNA of subjects with type 2 diabetes mellitus (DM). We found nine single nucleotide polymorphisms (SNPs) that were present with varying allele frequencies and pairwise linkage disequilibrium relationships in different ethnic groups." (as cited in article)

• Date created

  2004-02-01

• Subjects / Keywords

  • Endocrinology
  • Nutrition
  • Obesity
  • Metabolic disorders
  • Type 2 diabetes
  • Phosphoenolpyruvate carboxykinase (ATP)
  • Polymorphism
  • Transcription promoter
  • Canada

• Type of Item

  Article (Published)

• DOI

  https://doi.org/10.7939/r3-gsdq-p331

• License

  Attribution 4.0 International