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PolySearch: A web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites
Download2008
Cheng, Dean, Stothard, Paul, Damaraju, Sambasivarao, Wishart, David S., Knox, Craig, Young, Nelson
A particular challenge in biomedical text mining is to find ways of handling ‘comprehensive’ or ‘associative’ queries such as ‘Find all genes associated with breast cancer’. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe...
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Spring 2010
A reliable estimate of the amount of oil or gas in a reservoir is required for development decisions. Uncertainty in reserve estimates affects resource/reserve classification, investment decisions, and development decisions. There is a need to make the best decisions with an appropriate level...
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ReAS: Recovery of Ancestral Sequences for Transposable Elements from the Unassembled Reads of a Whole Genome Shotgun
Download2005
Ye, C., Wang, J., Li, S., Li, R., Wong, G.K.S., Ye, J., Yang, H., Han, Y., Yu, J.
We describe an algorithm, ReAS, to recover ancestral sequences for transposable elements (TEs) from the unassembled reads of a whole genome shotgun. The main assumptions are that these TEs must exist at high copy numbers across the genome and must not be so old that they are no longer...
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2005
Xia, Q., Chen, J., Dai, M., Ye, C., Wang, J., Li, S., Li, R., Zhou, Z., Ruan, J., Hu, Y., Yu, G., Yang, H., He, X., Yu, Jun, Xiang, Z., Yuan, H., Lu, C., Feng, T.
The Silkworm Knowledgebase (SilkDB) is a web-based repository for the curation, integration and study of silkworm genetic and genomic data. With the recent accomplishment of a ~6X draft genome sequence of the domestic silkworm (Bombyx mori ), SilkDB provides an integrated representation of the...
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Spring 2018
Teaching portfolios have been used by faculty in postsecondary institutions for summative and formative evaluations since the early 1980s (Knapper, 1995). Despite their proliferation, there remains much to be learned about the use of teaching portfolios and whether they are perceived as being...
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The mitochondrial genome of the hexactinellid sponge Aphrocallistes vastus: Evidence for programmed translational frameshifting
Download2008
Rosengarten, R.D., Sperling, E.A., Leys, S.P., Dellaporta, S.L., Moreno, M.A.
Background: Mitochondrial genomes (mtDNA) of numerous sponges have been sequenced as part of an ongoing effort to resolve the class-level phylogeny of the Porifera, as well as to place the various lower metazoan groups on the animal-kingdom tree. Most recently, the partial mtDNA of two glass...
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2014
Rockwell, Geoffrey, Chartier, Ryan, Simpson, John, Dyrbye, Amy
What can we learn from the discourse around text tools? More than might be expected. The development of text analysis tools has been a feature of computing in the humanities since IBM supported Father Busa's production of the Index Thomisticus (Tasman 1957). Despite the importance of tools in the...
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2002
Clark, A.M., MacIntyre, P.D., Sharp, C.
Access to health care should be determined by clinical need and not by age. Older people form an increasing proportion of the general population and of those with coronary heart disease, but compared with younger people they are less likely to be invited for cardiac rehabilitation programmes and...
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Fall 2016
Background. Tools and resources (TRs) can help to prevent obesity in children, particularly in settings that are accessible to families and well-aligned with chronic disease prevention, such as primary care. To date, little is known about the TRs that primary care providers (PCPs) currently use...