SilkDB: A knowledgebase for silkworm biology and genomic

• Author(s) / Creator(s)

  • Xia, Q.
  • Chen, J.
  • Dai, M.
  • Ye, C.
  • Wang, J.
  • Li, S.
  • Li, R.
  • Zhou, Z.
  • Ruan, J.
  • Hu, Y.
  • Yu, G.
  • Yang, H.
  • He, X.
  • Yu, Jun
  • Xiang, Z.
  • Yuan, H.
  • Lu, C.
  • Feng, T.

• The Silkworm Knowledgebase (SilkDB) is a web-based repository for the curation, integration and study of silkworm genetic and genomic data. With the recent accomplishment of a ~6X draft genome sequence of the domestic silkworm (Bombyx mori ), SilkDB provides an integrated representation of the large-scale, genome-wide sequence assembly, cDNAs, clusters of expressed sequence tags (ESTs), transposable elements (TEs), mutants, single nucleotide polymorphisms (SNPs) and functional annotations of genes with assignments to InterPro domains and Gene Ontology (GO) terms. SilkDB also hosts a set of ESTs from Bombyx mandarina, a wild progenitor of B.mori, and a collection of genes from other Lepidoptera.Comparative analysis results between the domestic and wild silkworm, between B.mori and other Lepidoptera, and between B.mori and the two sequenced insects, fruitfly and mosquito, are displayed by using B.mori genome sequence as a reference framework. Designed as a basic platform, SilkDB strives to provide a comprehensive knowledgebase about the silkworm and present the silkworm genome and related information in systematic and graphical ways for the convenience of in-depth comparative studies. SilkDB is publicly accessible at http://silkworm.genomics.org.cn.

• Date created

  2005

• Subjects / Keywords

  • Sequences
  • Resources
  • Databases
  • DNA
  • Bombyx-mori

• Type of Item

  Article (Published)

• DOI

  https://doi.org/10.7939/R32G3F

• License

  The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use permissions, please contact journals.permissions@oupjournals.org. © 2005, the authors