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Skip to Search Results- 2Miyashita, Tetsuto
- 1Abdrabou, Abdalla
- 1Adams, Emily
- 1Anderson-Baron, Matthew N
- 1Aulakh, Amit
- 1Baedke, Jessica
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A comprehensive assessment of peroxisome biology: ER-dependent peroxisome proliferation control, evolution of organelle inheritance in yeast and a Drosophila model system of Zellweger syndrome
DownloadFall 2013
The modern eukaryotic cell is a meshwork of encapsulating membranes that compartmentalize many distinct biochemical processes. It is complex. This complexity facilitates the many unique and diverse processes that aid the eukaryote in its growth, division and adaptation to its environment. A...
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Spring 2022
The endomembrane system is one of the hallmark features of all eukaryotes that distinguishes them from prokaryotes. Compared to bacteria and archaea, eukaryotic cells consist of biochemically and functionally distinct membranous compartments such as the endoplasmic reticulum, the Golgi apparatus,...
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Spring 2017
Cannabis use is a known risk factor for the development of psychotic disorders. Clinical and preclinical genetic studies provide growing evidence that genes related to dopamine signalling and neuroprotection, like COMT, are implicated in the cannabis-psychosis association. Considering the burden...
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Advanced agronomic practices to maximize feed barley (Hordeum vulgare L.) yield, quality, and standability in Alberta environments
DownloadFall 2017
The grain yields of feed barley (Hordeum vulgare L.) have increased at a slower rate than the yields of other major crops in Alberta, and seeded barley acres have declined over the past 20 years. Agronomic management and cultivar specific responses to management may provide solutions to increase...
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An ancestral role in de novo peroxisome assembly is retained by the divisional peroxin Pex11 in the yeast Yarrowia lipolytica
DownloadFall 2014
This thesis is on peroxisome evolution and reports my findings with regard to two major aspects of this process. First, I investigated the evolution of a peroxisomal protein family for which large expansions had been noted in diverse eukaryotes from a comparative genomic perspective and combined...
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Fall 2019
Here I describe new oviraptorosaur specimens and add to our knowledge of the anatomy, growth, behaviour, ecology, and evolution of oviraptorosaurs. Oviraptorosaurs were a diverse group of theropods known from a long history of discovery and a relatively abundant fossil record. Most analyses...
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Fall 2017
Flaviviruses are important human pathogens that have an enormous impact on global health. Examples that have been studied in my research include dengue virus (DENV), West Nile virus (WNV) and most recently, Zika virus (ZIKV). Currently, there are very few vaccines against or therapeutic...
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Anti-Cancer Mechanism of Trastuzumab via Blocking Nuclear HER2 Function and Epigenetic Mechanism of Resistance
DownloadSpring 2020
HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...
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Fall 2010
Improving feed efficiency has become a top priority in beef cattle production because of the rapidly increasing cost of feed provision. However, because of the expense associated with collecting individual animal feed intake data, only a relatively small number of animals have been tested,...