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Skip to Search Results- 14Etalons
- 12Stimuli-Responsive Polymers
- 6Photonic Materials
- 4Phase-Transition
- 3Poly (N-isopropylacrylamide)-Based Microgels
- 3Poly(N-Isopropylacrylamide)-Based Microgels
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Controlled drug release from the aggregation–disaggregation behavior of pH-responsive microgels
Download2014-01-01
Gao, Y., Ahiabu, A., Serpe, M. J.
In this submission, two independent sets of microgels were synthesized that exhibit pH responsivity over different solution pH ranges. The microgels were synthesized by copolymerizing two different comonomers with poly(N-isopropylacrylamide) (pNIPAm). The microgels copolymerized with acrylic acid...
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Controlled drug release from the aggregation–disaggregation behavior of pH-responsive microgels
Download2014-01-01
Gao, Yongfeng, Ahiabu, Andrews, Serpe, Michael J.
In this submission, two independent sets of microgels were synthesized that exhibit pH responsivity over different solution pH ranges. The microgels were synthesized by copolymerizing two different comonomers with poly(N-isopropylacrylamide) (pNIPAm). The microgels copolymerized with acrylic acid...
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2015
Guo, Siyuan, Zhang, Qiang M., Serpe, Michael J., Wei, Menglian, Gao, Yongfeng
A device constructed by sandwiching a thin film of poly(N-isopropylacrylamide)-co-acrylic acid (pNIPAmco-AAc) microgels between two thin layers of Au (all on a glass support) was used as a novel platform for controlled release of small molecules (drugs). In this submission, the model drug tris...
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Enzyme-assisted polymer film degradation-enabled biomolecule sensing with poly (N-isopropylacrylamide)-based optical devices
Download2018-01-01
Zhang, Wei, Wei, Menglian, Carvalho, Wildemar S. P., Serpe, Michael J.
A biosensor for mouse Immunoglobulin G (IgG) was generated from responsive polymer-based interference filters (etalons). To accomplish this, an excess amount of alkaline phosphatase-modified goat anti-mouse IgG (AP-GAM, F(ab’)2 fragment specific to mouse IgG) was added to mouse IgG, and allowed...
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Isolation of RNA from a mixture and its detection by utilizing a microgel-based optical device
Download2018-01-01
Islam, Molla R., Azimi, Shakiba, Teimoory, Faranak, Loppnow, Glen R., Serpe, Michael J.
In this investigation, we show that RNA can be separated from a solution containing DNA and RNA and the isolated RNA can be detected using poly (N-isopropylacrylamide-co-N-(3-aminopropyl) methacrylamide hydrochloride) microgel-based optical devices (etalons). The isolation of RNA was accomplished...
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2015
Berg, Darren, Mugo, Samuel M., Zhang, Qiang M., Serpe, Michael J.
Lipase-modified pH-responsive poly(N-isopropylacrylamide)-based microgels were synthesized. An optical device was subsequently fabricated by sandwiching the enzyme loaded responsive microgels between two thin Au layers, and their response to triolein, a model triglyceride, was investigated. The...
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2017-01-01
Zhang, Qiang, Colazo, Juan, Berg, Darren, Mugo, Samuel M., Serpe, Michael J.
Nanogels with a biomolecular coating (biocoating) were shown to be capable of triggered delivery of anticancer drug Doxorubicin. The biocoating was formed utilizing binding between glycogen and the tetra-functional lectin Concanavalin A, which can be triggered to disassemble (and release) upon...
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Penetration of polyelectrolytes into charged poly (N-isopropylacrylamide) microgel layers confined between two surfaces
Download2013-01-01
Islam, Molla R., Serpe, Michael J.
pH and temperature sensitive poly(N-isopropylacrylamide) (pNIPAm) microgel-based etalons were fabricated by sandwiching a “monolithic” microgel layer between two semitransparent, 15 nm Au layers. The devices exhibit visual color and multipeak reflectance spectra, both of which primarily depend on...
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2012
Poly (N-isopropylacrylamide) (pNIPAm) is one of the most completely studied “smart” polymers due to its unique reversible thermoresponsivity. That is, when pNIPAm in water is heated > ~31°C, it transits from a random coil to a globule conformation; this transition is reversed when T < ~31°C. This...
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2012-05-09
Poly (N-isopropylacrylamide) (pNIPAm) is one of the most completely studied “smart” polymers due to its unique reversible thermoresponsivity. That is, when pNIPAm in water is heated > ~31°C, it transits from a random coil to a globule conformation; this transition is reversed when T < ~31°C. This...