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Skip to Search Results- 4Löbenberg, Raimar
- 3Azarmi, Shirzad
- 3Field, Catherine J.
- 3Roa, Wilson H.
- 2Al-Hallak, MHD Kamal
- 2Ametaj, Burim N.
- 19Graduate and Postdoctoral Studies (GPS), Faculty of
- 19Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 9Agricultural, Food and Nutritional Science, Department of
- 9Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 6Pharmacy and Pharmaceutical Sciences, Faculty of
- 6Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy and Pharmaceutical Sciences)
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Innate immunity and carbohydrate metabolism alterations precede occurrence of subclinical mastitis in transition dairy cows
Download2015
Dervishi, Elda, Dunn, Suzana M., Zhang, Guanshi, Ametaj, Burim N., Hailemariam, Dagnachew
Background This study examined whether activation of innate immunity and alterations of carbohydrate and lipid metabolism precede development of subclinical mastitis (SCM). Methods Blood samples were collected from the coccygeal vein from 100 Holstein dairy cows at -8, -4, disease diagnosis week,...
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Fall 2016
Macrophages are the primary cells of innate immunity that provide the first line of defence against any external stimuli. Their phagocytic properties enable them to engulf invading microbes or foreign particles. The phagocytic capability of macrophages plays a major role in interfering with drug...
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Nanodelivery of Novel Inhibitors of ERCC1/XPF for sensitizing colorectal cancer cell to platinum drugs
DownloadSpring 2023
This project's long-term goal is to increase the efficacy of genotoxic therapeutics through thesensitization of cells to DNA-damaging therapy ahead of the treatment. The focus of this projectwas on the enhancement of platinum-based chemotherapeutics in colorectal cancer usingcolorectal cancer...
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Spring 2012
The present thesis describes preliminary studies required for evaluating silicon nanocrystals (Si-NCs) as photothermal (PT) therapy agents and drug delivery vehicles. Group 14 semiconductor NCs are of particular interest for these applications because of their tailorable optical response and...
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Poly n-butylcyanoacrylate (PNBCA) nanocapsules as a carrier for NSAIDs: in vitro release and in vivo skin penetration
Download2003
Kubo, W., Takahashi, A., Miyazaki, S., Löbenberg, R., Bachynsky, J.
Abstract: Purpose: The aim of this work was to prepare poly n-butylcyanoacrylate (PNBCA) nanocapsules loaded with indomethacin and to evaluate the ability of this carrier system to deliver the drug systemically after its topical application. Methods: Poly n-butylcyanoacrylate (PNBCA) nanocapsules...
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Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate
Download2015
Zhao, Yuan Y., McMullen,Todd P. W. , Brindley, David N., Curtis, Jonathan M., Benesch, Matthew G. K.
Autotaxin (ATX) is a secreted enzyme, which produces extracellular lysophosphatidate (LPA) from lysophosphatidylcholine (LPC). LPA activates six G protein-coupled receptors and this is essential for vasculogenesis during embryonic development. ATX is also involved in wound healing and...
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Fall 2017
Inflammation is generally considered to be a protective response, however the effects of inflammation can also be harmful and even fatal. The study of regulating the inflammatory response in damaged tissue by using engineered biomaterials is not only essential for enhancing the biocompatibility...