Search
Skip to Search Results- 1Abbasi Dezfouli, Meysam
- 1Abdulsalam Alharbi
- 1Aktary, Zackie M
- 1Alolayan, Waad Riyad
- 1Alshamsan, Aws
- 1Amritpal Singh Bhullar
- 8Department of Oncology
- 8Faculty of Pharmacy and Pharmaceutical Sciences
- 5Department of Agricultural, Food, and Nutritional Science
- 3Department of Medical Microbiology and Immunology
- 3Faculty of Nursing
- 3Faculty of Rehabilitation Medicine
- 4Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 3Foley, Edan (Medical Microbiology and Immunology)
- 2McNeely, Margaret (Rehabilitation Medicine)
- 2Uludag, Hasan (Chemical and Materials Engineering)
- 1Alasdair Syme (Oncology)
- 1Backhouse, Christopher J. (Electrical and Computer Engineering)
-
Cognitive Dysfunction in non-Hodgkin's Lymphoma Patients Treated with Front-Line Chemotherapy
DownloadSpring 2015
Despite the research to date, the characteristics and impact of cognitive dysfunction (CD) in cancer patients following chemotherapy is still not well understood. It is estimated approximately 20% of patients will manifest measurable cognitive deficits on neuropsychological testing...
-
Fall 2015
There is a concern that brain tumours are underreported in the Alberta Cancer Registry (ACR), yet no studies have been performed to investigate this issue. This study addresses the concern of underreporting of brain tumours in the ACR by assessing case ascertainment of primary brain tumours cases...
-
Comparison of tooth loss between intensity modulated and non-intensity modulated radiotherapy in head and neck cancer patients
DownloadFall 2011
Advanced radiotherapy (RT) systems (intensity modulated radiotherapy, IMRT) is widely used to treat head and neck cancer. A combination of radiation and chemotherapy potentially increases toxicity as well as dental complications. Tooth loss was retrospectively assessed using oral cavity,...
-
Fall 2009
The analysis of wide-angle cellular light scattering patterns is a challenging problem. Small changes to the organization, orientation, shape, and optical properties of scatterers and scattering populations can significantly alter their complex two-dimensional scattering signatures. Because of...
-
Cone-Beam Computed Tomography Evaluation of Oropharyngeal Airway Dimensions in Adolescents with Maxillary Transverse Deficiency
DownloadFall 2012
Objectives: The objective of this study is to analyze cone-beam computed tomography (CBCT) images to measure changes in oropharyngeal airway (OPA) dimensions after treatment with rapid maxillary expansion (RME), and compare these changes with those from a matched control group. Methods: This...
-
Deciphering the mechanism(s) which limit reovirus spread in resistant lung and HNSCC cancer cells
DownloadFall 2016
Reovirus is a naturally benign virus that preferentially replicates in transformed cells and is currently undergoing clinical trials as a promising oncolytic therapy. In normal mouse fibroblasts, transformation by constitutively activated Ras oncogene is sufficient to promote reovirus infection....
-
Delivery of STAT3 inhibitor cucurbitacins to tumor by polymeric nano-carriers : Implications in cancer chemo- and immunotherapy
DownloadFall 2009
Signal Transducer and Activator of Transcription 3 (STAT3), a common oncogenic mediator, is constitutively activated in many types of human cancers and plays a critical role in tumor growth and cancer immune evasion. The focus of this dissertation is the delivery of STAT3 inhibitor cucurbitacins...
-
Development of Novel Polymeric Micellar DACHPt for Enhanced Platinum Based Chemotherapy in Colorectal Cancer
DownloadSpring 2019
One of the major limitations of chemotherapy in cancer treatment is the side effects of anti-cancer drugs. This happens due to non-selective distribution of most standard chemotherapies, and their action on cancer and all normal dividing cells. The objective of this project is to develop a novel...
-
Development of Poly(ethylene oxide)-block-poly(ε-caprolactone) based Micelles for Tumor Targeted Drug and siRNA Delivery
DownloadFall 2015
The use of nanotechnology has made significant advancements in cancer diagnosis and treatment. Polymeric micelles are a relatively new generation of nanocarriers mostly intended for the delivery of hydrophobic drugs. In this thesis, our objective was to develop an optimized polymeric micellar...
-
Fall 2013
The aim of this work is to develop an effective non-viral carrier and to identify suitable gene targets that would induce apoptosis specifically in lymphoma cells upon down-regulation with short interfering RNA (siRNA). Lymphoma is common in children and young adults, and although survival rate...