Comparison of tooth loss between intensity modulated and non-intensity modulated radiotherapy in head and neck cancer patients

  • Author / Creator
    Beesley, Richelle Marie
  • Advanced radiotherapy (RT) systems (intensity modulated radiotherapy, IMRT) is widely used to treat head and neck cancer. A combination of radiation and chemotherapy potentially increases toxicity as well as dental complications. Tooth loss was retrospectively assessed using oral cavity, oropharyngeal and nasopharyngeal cancer patients. Clinical photographs were used to determine differences between non-intensity modulated RT and IMRT. Subject data were collected pre – post RT from 2000 – 2010. Due to the paucity in the data, only the first two years after RT could not be included in the final analysis. Additionally, risk factors related to tooth loss were explored between treatment groups. While the number of teeth lost in both groups was shown to be similar, statistically there were no between group differences up to two years after RT. Further investigations are necessary to increase the sample size and timeframe after RT treatment to determine the clinical implications of these dental changes.

  • Subjects / Keywords
  • Graduation date
  • Type of Item
  • Degree
    Master of Science
  • DOI
  • License
    This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.
  • Language
  • Institution
    University of Alberta
  • Degree level
  • Department
    • Faculty of Medicine and Dentistry
  • Supervisor / co-supervisor and their department(s)
    • Compton, Sharon (Dentistry)
    • Wolfaardt, Johan (Surgery)
  • Examining committee members and their departments
    • Parliament, Matthew (Radiation Oncology)
    • Rieger, Jana (Rehabilitation)
    • Seikaly, Hadi (Surgery)