Search
Skip to Search Results- 1Abbasi Dezfouli, Meysam
- 1Abdulsalam Alharbi
- 1Aktary, Zackie M
- 1Alolayan, Waad Riyad
- 1Alshamsan, Aws
- 1Amritpal Singh Bhullar
- 8Department of Oncology
- 8Faculty of Pharmacy and Pharmaceutical Sciences
- 5Department of Agricultural, Food, and Nutritional Science
- 3Department of Medical Microbiology and Immunology
- 3Faculty of Nursing
- 3Faculty of Rehabilitation Medicine
- 4Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 3Foley, Edan (Medical Microbiology and Immunology)
- 2McNeely, Margaret (Rehabilitation Medicine)
- 2Uludag, Hasan (Chemical and Materials Engineering)
- 1Alasdair Syme (Oncology)
- 1Backhouse, Christopher J. (Electrical and Computer Engineering)
-
Fall 2013
The use of nanotechnology in pharmaceutical development has progressed significantly in recent decades. This rapid advancement is driven by crucial need for improving the performance of present diagnostic and therapeutic modalities, as well as development of a new class of delivery systems for...
-
Spring 2015
Protein silencing by small interfering RNA (siRNA) is a promising treatment strategy for cancer as over-expression of proteins is largely responsible for cancer cells’ infinite proliferation, evasion of cell death and multi-drug resistance. However, siRNAs require a carrier as their biological...
-
Spring 2018
Renal cell carcinoma comprises approximately 2-3% of all malignancies, with the majority, approximately 70%, being clear cell renal cell carcinoma (ccRCC). ccRCC features many cancer hallmarks such as suppressed mitochondrial glucose oxidation, apoptosis-resistance, angiogenesis, immune evasion,...
-
Microtubules and Energy Metabolism: Targets for Standard, Combination, and Novel Therapeutic Interventions and Monitoring of Cancer
DownloadSpring 2016
The challenge of understanding and treating cancer has proven to be exceedingly complex. At this juncture, understanding cancer from the perspective of a breakdown of a complex cooperative system using a biophysical analysis may aid in improved treatments and prevention of this disease. In any...
-
Molecular Dynamics Simulations of Polyethylenimine Mediated Nucleic Acid Complexation with Implications for Non-viral Gene Delivery
DownloadSpring 2013
Gene therapy is a promising therapeutic technique that involves delivering nucleic acids into cells. Polycations have evolved into a major category of gene carriers. Polyethylenimine (PEI) is one of the most effective polycationic carriers. Furthermore, modifying PEI with certain lipophilic...
-
Fall 2013
Plakoglobin (γ-catenin) is a member of the Armadillo family of proteins and a homolog of β-catenin with similar dual adhesive and signaling functions. The adhesive function of these proteins is mediated by their interactions with cadherins and their signaling function by association with various...
-
Molecular imaging of cyclooxygenase-2 (COX-2) and autotaxin (ATX) in cancer using positron emission tomography (PET)
DownloadFall 2020
Positron emission tomography (PET) relies on the use of β+-emitting radionuclide-bearing molecules congregating and decaying at a specific site of interest. Use of these molecules, called radiotracers, which target common tumor characteristics has become a pillar in the diagnosis of cancer and...
-
Muscle Abnormalities in cancer patients: Exploring the biological characteristics of skeletal muscle of cancer patients
DownloadFall 2019
Computed tomography-derived muscle measures of sarcopenia and low muscle radiodensity have been associated with poor outcomes in cancer patients, however, the biological characteristics of the muscle in this population are not well understood. This research was conducted to first evaluate muscle...
-
Oropharyngeal dimensional changes following maxillary expansion with two different appliances: a CBCT study
DownloadFall 2019
Capenakas, Silvia Patricio Gianoni
Maxillary expansion is used to correct maxillary deficiencies, the most common technique is the Rapid Maxillary Expansion. Although there are several other treatment types depending on age such as surgery or archwire; maxillary expansion, have been related to the increase of the upper airway...
-
Physical Therapy Interventions for Children and Adolescents with Cancer: Collating the Evidence from Research and Clinical Practice
DownloadSpring 2018
Purpose: Children and adolescents with cancer who undergo cancer treatment are at high risk of developing serious late and long-term physical effects, many of which may be amenable to physical therapy (PT). Little is known about the benefits of PT or the services currently provided to address...