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Skip to Search Results- 26Graduate and Postdoctoral Studies (GPS), Faculty of
- 26Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 8Biological Sciences, Department of
- 8Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 3Agricultural, Food and Nutritional Science, Department of
- 3Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Spring 2010
This thesis presents Pathway Informed Analysis (PIA), a classification method for predicting disease states (diagnosis) from metabolic profile measurements that incorporates biological knowledge in the form of metabolic pathways. A metabolic pathway describes a set of chemical reactions that...
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An Adminstrative Data Merging Solution For Dealing With Missing Data In A Clinical Registry: Adaptation To ICD-9 to ICD-10
Download2008
Humphries, K., Norris, C.M., Quan, H., Galbraith, P.D., Southern, D.A., Gao, M., Knudtson, M.L., Ghali, W.A., Shrive, F.M.
Background: We have previously described a method for dealing with missing data in a prospective cardiac registry initiative. The method involves merging registry data to corresponding ICD-9-CM administrative data to fill in missing data 'holes'. Here, we describe the process of translating our...
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Annual Dispersal of Endangered Burrowing Owls (Athene cunicularia): Implications for Estimating Survival
DownloadSpring 2022
The migratory population of Burrowing Owl (Athene cunicularia) in Canada has undergone significant declines over the past five decades. Monitoring of Burrowing Owl includes estimation of annual survival which is predominantly obtained using mark-recapture data. Survival is calculated based on...
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Arctic cod (Boreogadus saida) hatching in the Hudson Bay system: Testing of the freshwater winter refuge hypothesis
Download2022-01-01
Schembri, Sarah, Deschepper, Inge, Myers, Paul G., Sirois, Pascal, Fortier, Louis, Bouchard, Caroline, Maps, Frederic
Buoyant Arctic cod (Boreogadus saida) eggs are found at the surface or at the ice-water interface in winter. While winter temperatures in saline waters fall below 0 degrees C, the temperature in areas affected by under-ice river plumes is slightly higher. Under-ice river plumes may therefore...
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Biology of Caloptilia fraxinella (Lepidoptera: Gracillariidae) on ornamental green ash, Fraxinus pennsylvanica (Oleaceae)
Download2009
Abstract: The ash leaf cone roller, Caloltilia firaxinella (Ely), is a leaf-mining moth that has recently become a significant pest of horticultural ash, Fraxinus L., species in communities throughout the western prairie provinces of Canada. The study examines the spatial and temporal within-host...
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Cancer-associated malnutrition, cachexia and sarcopenia: the skeleton in the hospital closet 40 years later
Download2016-01-20
Ryan, Aoife M., Power, Derek G., Daly, Louise, Cushen, Samantha J., Ní Bhuachalla, Ēadaoin, Prado, Carla M.
An awareness of the importance of nutritional status in hospital settings began more than 40 years ago. Much has been learned since and has altered care. For the past 40 years several large studies have shown that cancer patients are amongst the most malnourished of all patient groups. Recently,...
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Fall 2016
Survival data is mostly analyzed using Cox proportional hazards model to identify factors associated with survival time of patients. However recently random survival forest (RSF), a non-parametric method for ensemble estimation constructed by bagging of classification trees for survival data, is...
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Fall 2021
One third of all deaths in Canada are due to cardiovascular diseases, including heart failure. Cardiovascular diseases have a considerable economic burden, and drastically impact the health and quality of life of Canadians. Heart failure (HF) is a clinical condition where the heart is unable to...
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Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22
2013
Pfrengle, F., Kawasaki, N., Paulson, J. C. , Macauley, M. S.
Differentiation of self from nonself is indispensable for maintaining B cell tolerance in peripheral tissues. CD22 and Siglec-G (sialic acid-binding Ig-like lectin G) are two inhibitory coreceptors of the BCR that are implicated in maintenance of tolerance to self Ags. Enforced ligation of CD22...