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Skip to Search Results- 5Wu, Jianping
- 4Chakrabarti, Subhadeep
- 3Majumder, Kaustav
- 3Proctor, Spencer D.
- 2AlZahal, Ousama
- 2Curtis, Jonathan M.
- 53Graduate and Postdoctoral Studies (GPS), Faculty of
- 53Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 21Agricultural, Food and Nutritional Science, Department of
- 21Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Medicine and Dentistry, Faculty of
- 2Pharmacy and Pharmaceutical Sciences, Faculty of
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Vaccenic and elaidic acid modify plasma and splenocyte membrane phospholipids and mitogen-stimulated cytokine production in obese insulin resistant JCR:LA-cp rats
Download2010
Ruth, Megan R., Reaney, Martin J., Vine, Donna F., Goruk, Susan, Yu, Howe-Ming, Field, Catherine J., Proctor, Spencer D., Wang, Ye
This study assessed the long-term effects of dietary vaccenic acid (VA) and elaidic acid (EA) on plasma and splenocyte phospholipid (PL) composition and related changes in inflammation and splenocyte phenotypes and cytokine responses in obese/insulin resistant JCR:LA-cp rats. Relative to lean...
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Drug-disease interaction: effect of inflammation on the pharmacological response to calcium channel blockers
DownloadFall 2010
The present research is focused on the topic of inflammation-drug interaction. Inflammation complicates many human diseases and conditions ranging from obesity to cancer. Therefore, the study of the effect of inflammation on drug pharmacokinetics and pharmacodynamics is pivotal. First, we tested...
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Fall 2010
Abstract: Introduction: Partial bladder outlet obstruction (pBOO) is a ubiquitous problem that results in renal damage. We hypothesize that change in the bladder progresses over time. Methods: Fischer rats underwent surgical pBOO for 2, 4, 8, or 13 weeks and were compared to shams. Urodynamic...
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Unique cellular interactions between the obligate intracellular bacteria Wolbachia pipientis and its insect host
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Wolbachia are maternally inherited obligate intracellular bacteria found in arthropods, where they induce feminization, male-killing, parthenogenesis, and cytoplasmic incompatibility (CI). CI is conditional male sterility, in which Wolbachia-infected males successfully mate with infected females,...
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The analysis of cytokine regulation of macrophage antimicrobial responses of the goldfish (Carassius auratus L.)
DownloadFall 2011
Inflammation is a highly regulated immune response to tissue damage, infiltrating pathogens or both. Cells of the myeloid lineage such as macrophages are indispensable for the initiation, progression and resolution of inflammation. Macrophages possess an armamentarium of antimicrobial responses...
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Spring 2011
Niemann-Pick Type C (NPC) disease is an autosomal recessive disorder that results in accumulation of unesterified cholesterol in late endosomes/lysosomes (LE/Ls), leading to progressive neurodegeneration and premature death. Microglia are resident immune cells of the central nervous system, which...
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2011
Boutin, Hervé, Crossman, David, Smigova, Alison, Drake, Caroline, Allan, Stuart M., Francis, Sheila, Gerhard, Alexander, Jones, Matthew S., Hinz, Rainer, Kassiou, Michael, Hopkins, Stephen J., Vail, Andy, Herholz, Karl, Tyrrell, Pippa J., Selvarajah, Johann R., Rothwell, Nancy J., Julyan, Peter, Georgiou, Rachel F., Brown, Gavin, Maroy, Renaud, Denes, Adam, Russell, James C., Proctor, Spencer D., McColl, Barry W., Prenant, Christian, Hulme, Sharon
Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity are associated with increased risk of stroke, which suggests that systemic inflammation may contribute to the development of stroke in humans. The hypothesis that systemic inflammation may induce brain...
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The soil microbial community and grain micronutrient concentration of historical and modern hard red spring wheat cultivars grown organically and conventionally in the black soil zone of the Canadian prairies
Download2011
Thavarajah, Dil, Clapperton, M. Jill, Frick, Brenda, Quideau, Sylvie A., Hucl, Pierre J., Nelson, Alison G., Spaner, Dean M.
Micronutrient deficiencies in the diet of many people are common and wheat is a staple food crop, providing a carbohydrate and micronutrient source to a large percentage of the world’s population. We conducted a field study to compare five Canadian red spring wheat cultivars (released over the...
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Exploring the role of the thioredoxin system, peroxiredoxins and glutaredoxins in aluminum and cadmium tolerance in yeast and Arabidopsis thaliana
DownloadFall 2011
Aluminum (Al) and cadmium (Cd) are non-redox active metal ions of agricultural importance. Both are able to induce oxidative damage as a mechanism of toxicity. To increase our understanding of the mechanisms of Al and Cd toxicity and tolerance in plants, the potential role of antioxidant enzymes...