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Skip to Search Results- 13Cryopreservation
- 11Statistical analysis
- 9Articular cartilage
- 7Vitrification
- 5Digital humanities
- 5History of digital humanities
- 12Graduate and Postdoctoral Studies (GPS), Faculty of
- 12Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 11Chemical and Materials Engineering, Department of
- 11Chemical and Materials Engineering, Department of/Research Articles and Materials (Chemical and Materials Engineering)
- 7Surgery, Department of
- 7Surgery, Department of/Orthopaedic Surgery
- 4Department of Chemical and Materials Engineering
- 3Department of Surgery
- 1Department of Biological Sciences
- 1Department of Civil and Environmental Engineering
- 1Department of Electrical and Computer Engineering
- 1Department of Physical Therapy
- 1Adesida, Adetola (Surgery)
- 1Adesida, Adetola B. (Surgery)
- 1Bagnall, Keith (Department of Surgery)
- 1Boluk, Yaman (Civil and Environmental Engineering)
- 1Elliott, Janet A. W. (Chemical & Materials Engineering and Laboratory Medicine & Pathology)
- 1Elliott, Janet A.W. (Chemical and Materials Engineering)
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Fall 2015
Osteoarthritis, a disease resulting in the breakdown of cartilage and bone within joints, is a global burden that is growing in scope. There is no cure for osteoarthritis, and the current treatments are all lacking in some form or another. One treatment which attempts to prevent degeneration of...
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2014-09-26
Rekieh, K., Abazari, A., Elliott, J.A., Jomha, N.M., Law, G.K., McGann, L.E.
Objective: Osteochondral allografting is an effective method to treat large osteochondral defects but difficulties in tissue preservation have significantly limited the application of this technique. Successful cryopreservation of articular cartilage (AC) could improve the clinical availability...
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2005
Cruden, D. M., Morgenstern, N. R., El-Ramly, H.
A probabilistic slope analysis methodology based on Monte Carlo simulation using Microsoft Excel and @Risk software is applied to investigate the failure of the Shek Kip Mei cut in Hong Kong. The study demonstrates the techniques used in quantifying uncertainties in shear strength of granitic...
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Fall 2015
Cryopreserving cells for human health therapeutics is a multidisciplinary process with great complexity. Cryopreservation of human umbilical vein endothelial cells (HUVECs) has facilitated vascular biology research since they were first isolated in 1973 [59]; however identifying key variables to...
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Fall 2016
Articular cartilage injury is a major risk factor for the development of osteoarthritis, a condition that results in significant patient morbidity and substantial cost to the healthcare system. Due to the limited capacity of articular cartilage to regenerate, early intervention is required to...
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Statistical prediction of the vitrifiability and glass stability of multi-component cryoprotective agent solutions.
Download2010
Forbes, J. F., Law, G. K., Weiss, A. D., Scheuerman, A., McGann, L. E., Elliott, J. A., Jomha, N. M.
Long-term biologic storage of articular cartilage has proven elusive due to cellular degradation over time or acute damage during attempts at cryopreservation. Vitrification is one option that may result in successful cryopreservation but difficulty with cryoprotective agent (CPA) toxicity at...
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The role of cultured chondrocytes and mesenchymal stem cells in the repair of acute articular cartilage injuries
DownloadSpring 2010
Osteoarthritis (OA) is a disease that has significant individual, social, and economic impact worldwide. Although many etiologies lead to the eventual development of OA, one potentially treatable cause is the acute articular cartilage (AC) injury. These injuries are common and have a poor...
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2013
Arppe, Antti, Newman, John, Han, Weifang
Shanghainese is an extremely topic-prominent language with many topic markers in competition with one another, often without any obvious basis for the selection of one topic marker over another. We explore the influence of five variables on the five most frequent topic markers in a corpus of...
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Versatile Polymer-Based Nanomedicines for Drug/Gene Delivery and Cell-based Therapy Applications
DownloadSpring 2021
Advances in polymer science and nanotechnology have allowed the development of biomaterials for cell-based applications, such as the delivery of a variety of drugs and genes, as well as supporting technologies, such as stem cell therapies, tissue engineering and cryopreservation. The progress in...
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2012
Elliott, J. A., Zhou, X., McGann, L. E., Adesida, A. B., Abazari, A., Law, G. K., Laouar, L., Forbes, J. F., Jomha, N. M., Maghdoori, B.
Articular cartilage injuries do not heal and large defects result in osteoarthritis with major personal and socioeconomic costs. Osteochondral transplantation is an effective treatment for large joint defects but its use is limited by the inability to store cartilage for long periods of time....