Search
Skip to Search Results- 20Older adults
- 18Alzheimer's disease
- 4Cognitive impairment
- 3Amyloid precursor protein
- 2Amyloid beta
- 2Autophagy
-
Listening Deeply: A Narrative Inquiry into the Experiences of Older Adults in Relation to Place
DownloadFall 2014
While living alongside Grandma’s stories of growing older in a small rural town in Australia, I became interested in the stories she told in her living room and what it meant to grow older in a place Grandma called home. As I thought narratively about her stories, I woke to the possibility that...
-
Fall 2012
Parkinson’s disease (PD) involves the motor system and can lead to dementia. Dementia incidence among 102 non-demented participants (52 PD and 50 controls) followed prospectively over three years was assessed. Cognition was measured annually using the Clock Drawing Test (CDT), Mini-Mental State...
-
Fall 2012
BACKGROUND: Osteoporosis is a skeletal disease characterized by low bone mass and deterioration of bone, leading to increased bone fragility and risk of fracture. PURPOSE: The purpose of this research was to examine clinical utilization patterns and use of osteoporosis medications, and their...
-
Older Adults and Generativity: Developmental, Experimental, and Clinical Advances in Terror Management Theory
DownloadSpring 2013
Terror Management Theory (TMT) (Greenberg, Pyszczynski, & Solomon, 1986) offers an empirical framework to explore how human beings function despite their fear of death. TMT studies have shown that in order to buffer death anxiety, people strive to meet the standards of their cultural worldview. ...
-
Spring 2016
Poor oral health in older adults is identified as a major health issue. There are cumulative effects of oral diseases over time that may impact other health issues for older adults. Regular utilization of dental care is key to maintaining good oral health in later life; however, older adults...
-
Fall 2013
Although many policy frameworks, research definitions and programs on Healthy Aging are available in Canada and abroad, little is known about older adults’ perspectives on this topic. Given the steady increase of the numbers of older Canadians, as well as the diversity of their cultural...
-
Putative ante-mortem indicators of Alzheimer’s dementia: Analysis of fluid biomarker and neuroimaging studies
DownloadSpring 2019
Dementia is a clinical state, characterized by symptoms indicative of deterioration of memoryand cognitive functions that interferes with social or occupational functioning. According to2018 statistics, around 50 million people are living with dementia, and this number will increaseto 131.5...
-
Role of Glutamate and GABA in a mouse model expressing mutant human APP in the absence of NPC1 protein
DownloadSpring 2013
Cholesterol plays a critical role in Alzheimer’s disease (AD) pathogenesis, but the underlying mechanisms remain unclear. To address this issue we have generated a line of ANPC transgenic mice that overexpress mutant-human amyloid precursor protein in the absence of cholesterol transporting...