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- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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A genome-wide association study of fetal response to type 2 porcine reproductive and respiratory syndrome virus challenge
Download2016-02-05
Plastow, Graham, Ladinig, Andrea, Harding, John, Wang, Zhiquan, Wilkinson, James, Yang, Tianfu
Control of porcine reproductive and respiratory syndrome (PRRS) is economically important for the swine industry worldwide. As current PRRS vaccines do not completely protect against heterologous challenge, alternative means of control, including enhanced genetic resilience, are needed. For...
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Fall 2017
The emergence of high-throughput genomic data provides new opportunities for genetic analysis. Especially, in terms of genetic improvement of animals, genomic tools provide new tools for animal selection, while still suffering from some statistical issues due to the high-dimension of the genomic...
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2019-11-01
Parkins, John, Goddard, Ellen, Plastow, Graham, Carlyle, Cameron
NFRF-Exploration grant awarded 2020: Sustainability of the beef industry and sustainability of temperate grasslands are equally challenging currently. Beef cattle don’t typically graze on tidy fields of managed pasture, but instead graze complex landscapes with highly diverse vegetation and plant...
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Comparative transcriptomic analysis of rectal tissue from beef steers revealed reduced host immunity in Escherichia coli O157:H7 super-shedders
Download2016-03-09
McAllister, Tim A., Wang, Ou, Plastow, Graham, Stanford, Kim, Liang, Guanxiang, Guan, Le L., Selinger, Brent
Super-shedder cattle are a major disseminator of E. coli O157:H7 into the environment, and the terminal rectum has been proposed as the primary E. coli O157:H7 colonization site. This study aimed to identify host factors that are associated with the super-shedding process by comparing...
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Developing a genome-wide selection model for genetic improvement of residual feed intake and carcass merit in a beef cattle breeding program
Download2012
Zeng, ZhiYao, Moore, Stephen S., Lai, SongJia, Plastow, Graham, Tang, GuoQing, Wang, ZhiQuan, Ma, JiDeng, Li, XueWei
Residual feed intake (RFI) and carcass merit (CM) are both complex traits emerging as critical targets for beef genetic improvement. RFI and CM traits are difficult and expensive to measure and genetic improvement for these traits through traditional selection methods is not very effective....
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Discovery of Predictors of Mycoplasma hyopneumoniae Vaccine Response Efficiency in Pigs: 16S rRNA Gene Fecal Microbiota Analysis
Download2020-07-22
Munyaka, Peris M., Blanc, Fany, Estelle, Jordi, Lemonnier, Gaetan, Leplat, Jean-Jacques, Rossignol, Marie-Noelle, Jardet, Deborah, Plastow, Graham, Billon, Yvon, Willing, Benjamin P., Rogel-Gaillard, Claire
The gut microbiota comprises a large and diverse community of bacteria that play a significant role in swine health. Indeed, there is a tight association between the enteric immune system and the overall composition and richness of the microbiota, which is key in the induction, training and...
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Genome wide association studies (GWAS) identify QTL on SSC2 and SSC17 affecting loin peak shear force in crossbred commercial pigs
Download2016-02-22
Miar, Younes, Wang, Zhiquan, Kemp, Robert A., Boddicker, Nicholas, Yang, Tianfu, Plastow, Graham, Zhang, Chunyan, Charagu, Patrick, Bruce, Heather
Of all the meat quality traits, tenderness is considered the most important with regard to eating quality and market value. In this study we have utilised genome wide association studies (GWAS) for peak shear force (PSF) of loin muscle as a measure of tenderness for 1,976 crossbred commercial...
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Genomic Prediction of Piglet Responses to Infection with One or Two Porcine Reproductive and Respiratory Syndrome Virus Isolates
Download2018-01-01
Waide, Emily H., Tuggle, Christopher K., Serao, Nick V. I., Schroyen, Martine, Hess, Andrew, Rowland, Raymond R. R., Lunney, Joan K., Plastow, Graham, Dekkers, Jack C. M.
Genomic prediction of the pig’s response to the porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) would be a useful tool in the swine industry. This study investigated the accuracy of genomic prediction based on porcine SNP60 Beadchip data using training and validation datasets...
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Kinome profiling of peripheral blood mononuclear cells collected prior to vaccination reveals biomarkers and potential mechanisms of vaccine unresponsiveness in pigs
Download2020-12-01
Lipsit, Sean W. L., Wilkinson, James, Scruten, Erin, Facciuolo, Antonio, Denomy, Connor, Griebel, Philip J., Kusalik, Anthony, Plastow, Graham, Napper, Scott
Inter-individual variance in host immune responses following vaccination can result in failure to develop protective immunity leaving individuals at risk for infection in addition to compromising herd immunity. While developing more efficacious vaccines is one strategy to mitigate this problem,...
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Maternal and fetal predictors of fetal viral load and death in third trimester, type 2 porcine reproductive and respiratory syndrome virus infected pregnant gilts
Download2015-09-25
Wilkinson, Jamie M., Lunney, Joan K., Detmer, Susan E., Ladinig, Andrea, Harding, John C.S., Ashley, Carolyn, Plastow, Graham
Minimal research has focused on understanding mechanisms underlying porcine reproductive and respiratory syndrome virus (PRRSV) induced reproductive failure. We have completed a large-scale project investigating phenotypic and genotypic predictors of reproductive PRRS severity in which numerous...