Journal Articles (Chemistry)

2020-01-01

Bhattacharya, A., Qiu, Y., Bernard, G.M., Butler, S., Mar, A., Michaelis, V.K.

Glass-ceramics are an attractive oxide-based material routinely used for biomineral repair such as porcelain veneers in dental crown applications. The short- and long-range structure of a commercial glass-ceramic feldspar material, VITA VM9, has been investigated as a function of annealing...

2017-01-01

Zhang, Wei, Serpe, Michael J.

In this submission, we detail a new method for detecting mouse Immunoglobulin G (IgG) utilizing fluorophore-modified antibodies and antibody-modified magnetic microparticles. This was accomplished by adding an excess amount of fluorescein isothiocyanate (FITC)-modified goat anti-mouse IgG...

2013

Pfrengle, Fabian, Paulson, James C., Gale, Andrew J., Nycholat, Corwin M., von Drygalski, Annette, Rademacher, Christoph, Macauley, Matthew S.

Antibodies confer humoral immunity but can also be harmful when they target an autoantigen, alloantigen, allergen, or biotherapeutic. New strategies are needed for antigen-specific suppression of undesired antibody responses, particularly to T cell–dependent protein antigens, because they elicit...

2011-02-01

Nikolai A. Sinkov, Brandon M. Johnston, P. Mark L. Sandercock, and James J. Harynuk

Direct chemometric interpretation of raw chromatographic data (as opposed to integrated peak tables) has been shown to be advantageous in many circumstances. However, this approach presents two significant challenges: data alignment and feature selection. In order to interpret the data, the time...

2006

Mackereth, Cameron D., Graves, Barbara J., Macauley, Matthew S., Schärpf, Manuela, McIntosh, Lawrence P. , Blaszczak, Adam G., Errington, Wesley J.

Sumoylation regulates the activities of several members of the ETS transcription factor family. To provide a molecular framework for understanding this regulation, we have characterized the conjugation of Ets-1 with SUMO-1. Ets-1 is modified in vivo predominantly at a consensus sumoylation motif...

2011

Dingle, Tanis C., Szpacenko, Adam, Ng, Kenneth K.S., Kitov, Pavel, Klassen, John S., El-Hawiet, Amr, Kitova,Elena N., Mulvey, George L., Eugenio, Luiz, Armstrong, Glen D.

The binding of recombinant fragments of the C-terminal cell-binding domains of the two large exotoxins, toxin A (TcdA) and toxin B (TcdB), expressed by Clostridium difficile and a library consisting of the most abundant neutral and acidic human milk oligosaccharides (HMOs) was examined...

2011

El-Hawiet, Amr, Klassen, John S., Armstrong, Glen D., Dingle, Tanis C., Eugenio, Luiz, Mulvey, George L., Szpacenko, Adam, Ng, Kenneth K.S., Kitova,Elena N., Kitov, Pavel

The binding of recombinant fragments of the C-terminal cell-binding domains of the two large exotoxins, toxin A (TcdA) and toxin B (TcdB), expressed by Clostridium difficile and a library consisting of the most abundant neutral and acidic human milk oligosaccharides (HMOs) was examined...

2012

Sun, Nian, Klassen, John S., Bai, Yu, Liu, Lan, Xia, Li, Lowary, Todd L.

The interactions between 3-O-methyl-mannose polysaccharides (MMPs), extracted from Mycobacterium smegmatis (consisting of a mixture of MMP-10, -11, -12 and -13) or obtained by chemical synthesis (MMP-5s, -8s, -11s and -14s), and linear saturated and unsaturated fatty acids (FAs), and a commercial...

2012

Xia, Li, Sun, Nian, Klassen, John S., Liu, Lan, Bai, Yu, Lowary, Todd L.

The interactions between 3-O-methyl-mannose polysaccharides (MMPs), extracted from Mycobacterium smegmatis (consisting of a mixture of MMP-10, -11, -12 and -13) or obtained by chemical synthesis (MMP-5s, -8s, -11s and -14s), and linear saturated and unsaturated fatty acids (FAs), and a commercial...

2014

Howell, P. Lynne, Klassen, John S., Wolfram, Francis, Robinson, Howard, Kitova, Elena N., Codée, Jeroen D. C., Walvoort, Marthe T. C.

Pseudomonas aeruginosa is an opportunistic pathogen that forms chronic biofilm infections in the lungs of cystic fibrosis patients. A major component of the biofilm during these infections is the exopolysaccharide alginate, which is synthesized at the inner membrane as a homopolymer of 1–4-linked...